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动脉瘤性蛛网膜下腔出血的早期手术及总体预后

Early operation and overall outcome in aneurysmal subarachnoid hemorrhage.

作者信息

Ljunggren B, Säveland H, Brandt L, Zygmunt S

出版信息

J Neurosurg. 1985 Apr;62(4):547-51. doi: 10.3171/jns.1985.62.4.0547.

Abstract

Over a 3-year period, 251 individuals in a population of 1.46 million were known to have suffered an aneurysmal subarachnoid hemorrhage (SAH). Forty-three individuals (17%) were either found dead or were dead on arrival at a hospital or forensic department. Forty-nine patients (20%) were at no stage in their clinical course considered to be surgical candidates. Six patients (2% of the total series) were initially in good condition, but subsequently deteriorated during the acute phase and were not treated surgically. Nineteen poor-risk patients (8% of the total series) underwent emergency surgery because of a life-threatening intracerebral hematoma; 105 patients (42% of the total series or 69% of the surgically treated patients) were operated on at the acute stage, and 29 patients (11% of the total series or 19% of the surgically treated patients) underwent late surgery. Of the total series, 107 patients (42%) recovered without neurological deficits; the overall morbidity rate was 19%, and the mortality rate was 39%. Of 99 Grade I to III patients who were operated on at the acute stage, 76% recovered without neurological deficits, and 4% died. It is concluded that the overall outcome in aneurysmal SAH remains poor, mainly because of the large group of patients who are permanently devastated by their initial bleed.

摘要

在三年时间里,已知在146万人口中有251人发生了动脉瘤性蛛网膜下腔出血(SAH)。43人(17%)被发现死亡或在抵达医院或法医部门时已死亡。49名患者(20%)在其临床过程中的任何阶段都不被认为是手术候选者。6名患者(占总病例数的2%)最初情况良好,但随后在急性期病情恶化,未接受手术治疗。19名高危患者(占总病例数的8%)因威胁生命的脑内血肿接受了急诊手术;105名患者(占总病例数的42%或接受手术治疗患者的69%)在急性期接受了手术,29名患者(占总病例数的11%或接受手术治疗患者的19%)接受了延迟手术。在整个系列中,107名患者(42%)康复且无神经功能缺损;总体发病率为19%,死亡率为39%。在急性期接受手术的99名I至III级患者中,76%康复且无神经功能缺损,4%死亡。得出的结论是,动脉瘤性SAH的总体预后仍然很差,主要是因为有一大群患者因最初的出血而永久性致残。

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