Christie-de Jong Floor, Eberhardt Judith, Ling Jonathan, Kotzur Marie, Oyeniyi Olugbenga Samuel, Nnyanzi Lawrence, Kabuye John, Kalemba Martin, Robb Kathryn A
Faculty of Health Sciences and Wellbeing, School of Medicine, University of Sunderland, Sunderland, United Kingdom.
Centre for Applied Psychological Science, Teesside University, Middlesbrough, United Kingdom.
PLoS One. 2024 Dec 31;19(12):e0315288. doi: 10.1371/journal.pone.0315288. eCollection 2024.
Prostate cancer is the most common cancer in the UK and Black African-Caribbean men are twice as likely to develop prostate cancer as white men. These cancer inequalities need urgent tackling. Barriers to early diagnosis are complex and require complex solutions. Culturally-tailored, community-centred and participatory approaches show promise in tackling cancer inequalities. We aim to co-design a culturally appropriate intervention to tackle barriers to early diagnosis of prostate cancer for Black men in Scotland and the North-East of England using a community-centred participatory approach.
The PROCAN-B study is a mixed methods study set in Scotland and the North-East of England. A Public Involvement and Community Engagement (PICE) group (n = 12), is involved at every step of the research. Drawing on principles of the Integrated Screening Action model (I-SAM), the study has 8 objectives: 1) to explore barriers to early diagnosis of prostate cancer among Black men (45+) through focus groups (n = 12); 2) to co-design a culturally acceptable peer-led intervention to tackle barriers to early diagnosis of prostate cancer in Black men; 3) to train members of the community as 'peer-facilitators' (n = 8); 4) to deliver the intervention in each location, facilitated by peer-facilitators, with a purposive sample (n = 20) of Black men (45+); 5) to qualitatively evaluate the intervention through focus groups; 6) to refine the intervention based on qualitative feedback; 7) to pilot the refined intervention with another purposive sample (n = 40) through a cross-sectional survey pre- and post-intervention; 8) to qualitatively evaluate the refined intervention through focus groups to further refine the intervention.
Community-centred and culturally tailored interventions have potential to be effective in addressing barriers to early diagnosis of prostate cancer, and thus ultimately reduce morbidity and mortality rates through earlier diagnosis in Black communities.
前列腺癌是英国最常见的癌症，非洲 - 加勒比黑人男性患前列腺癌的可能性是白人男性的两倍。这些癌症方面的不平等现象亟待解决。早期诊断的障碍错综复杂，需要复杂的解决办法。针对特定文化、以社区为中心和参与式的方法在解决癌症不平等问题上显示出了前景。我们旨在采用以社区为中心的参与式方法，共同设计一种适合特定文化的干预措施，以解决苏格兰和英格兰东北部黑人男性前列腺癌早期诊断的障碍。
PROCAN - B研究是一项在苏格兰和英格兰东北部开展的混合方法研究。一个公众参与和社区参与（PICE）小组（n = 12）参与研究的每一个步骤。借鉴综合筛查行动模型（I - SAM）的原则，该研究有8个目标：1）通过焦点小组（n = 12）探索45岁及以上黑人男性前列腺癌早期诊断的障碍；2）共同设计一种文化上可接受的由同龄人主导的干预措施，以解决黑人男性前列腺癌早期诊断的障碍；3）培训社区成员成为“同伴促进者”（n = 8）；4）在每个地点由同伴促进者推动实施干预措施，对45岁及以上的黑人男性进行有目的抽样（n = 20）；5）通过焦点小组对干预措施进行定性评估；6）根据定性反馈完善干预措施；7）通过干预前后的横断面调查，对另一个有目的样本（n = 40）进行完善后的干预措施试点；8）通过焦点小组对完善后的干预措施进行定性评估，以进一步完善干预措施。
以社区为中心且针对特定文化的干预措施有可能有效解决前列腺癌早期诊断的障碍，从而最终通过在黑人社区更早诊断来降低发病率和死亡率。
