Maibvise Charles, Munangatire Takaedza, Tomas Nestor, Ashipala Daniel O, Dlamini Priscilla S
Department of Clinical, Pharmaceutical, Biological Sciences, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom.
Department of General Nursing, School of Nursing and Public Health, University of Namibia, Windhoek, Namibia.
PLoS One. 2024 Dec 31;19(12):e0316106. doi: 10.1371/journal.pone.0316106. eCollection 2024.
Campaigns to scale up Voluntary Medical Male Circumcision (VMMC) for the prevention of HIV transmission has been going on for years in selected Southern African countries, following recommendations from the World Health Organisations. Despite significant strides made in the initiative and its proven benefits, controversies surrounding the strategy have never ceased, and its future remains uncertain especially as some countries near their initial targets. Over the years, as the campaigns unfolded, a lot of insights have been generated in favour of continuing the VMMC campaigns, although some insights portray the impression that the strategy is not worthy of the risks and effort required, or that enough has been done, as the targets have now been achieved. This article proposes a scoping review that aims at synthesizing and consolidating that evidence into a baseline for a further systematic review aimed at developing sound recommendations for the future of the VMMC strategy for HIV prevention. The scoping review will target all scientific literature published on the Web of Science, Cochrane Library, Scopus, Science Direct, PubMed as well as grey literature from Google Scholar and WHO Institutional Repository for Information Sharing (IRIS) from the inception of the campaigns. The review shall be guided by Arksey and O'Malley's (2005) framework for scoping reviews, and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews (PRISMA-ScR) checklist shall be followed. Discussion of the findings is envisioned to yield evidence that can be further analysed to give insights about risk/cost-benefits ratios of the strategy at this point in time as well as best clinical practices for the VMMC procedure, to inform the future of the strategy. This protocol is registered with the Open Science Framework, registration ID https://doi.org/10.17605/OSF.IO/SFZC9.
根据世界卫生组织的建议，在选定的南部非洲国家开展扩大自愿男性包皮环切术（VMMC）以预防艾滋病毒传播的运动已经进行多年。尽管该倡议取得了重大进展并已证明其益处，但围绕该战略的争议从未停止，其未来仍不确定，尤其是一些国家接近其初始目标时。多年来，随着运动的展开，产生了许多支持继续开展VMMC运动的见解，尽管一些见解给人的印象是该战略不值得承担所需的风险和付出努力，或者认为已经做得足够了，因为目标现已实现。本文提出了一项范围综述，旨在将这些证据综合并巩固为进一步系统综述的基线，以便为VMMC预防艾滋病毒战略的未来制定合理建议。范围综述将针对自运动开始以来在科学网、考克兰图书馆、Scopus、科学Direct、PubMed上发表的所有科学文献，以及来自谷歌学术和世卫组织信息共享机构知识库（IRIS）的灰色文献。该综述将以阿克西和奥马利（2005年）的范围综述框架为指导，并遵循系统综述和元分析扩展的范围综述首选报告项目（PRISMA-ScR）清单。预计对研究结果的讨论会产生可进一步分析的证据，以深入了解此时该战略的风险/成本效益比以及VMMC程序的最佳临床实践，为该战略的未来提供参考。本方案已在开放科学框架注册，注册ID为https://doi.org/10.17605/OSF.IO/SFZC9。
