Poikonen-Saksela Paula, Karademas Evangelos, Vehmanen Leena, Utriainen Meri, Kondylakis Haridimos, Kourou Konstadina, Manikis Georgios C, Kolokotroni Eleni, Argyropaidas Panagiotis, Sousa Berta, Pat Horenczyk Ruth, Mazzocco Ketti, Mattson Johanna
Comprehensive Cancer Center Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Department of Psychology University of Crete, Rethymno, Greece.
Breast J. 2024 Aug 13;2024:8036696. doi: 10.1155/2024/8036696. eCollection 2024.
Despite excellent prognosis of early breast cancer, the patients face problems related to decreased quality of life and mental health. There is a need for easily available interventions targeting modifiable factors related to these problems. The aim of this study was to test the use of a new digital supportive intervention platform for early breast cancer patients. . Ninety-seven early breast cancer patients answered questions on wellbeing, exercise, and sociodemographic factors before systemic adjuvant treatment at the Helsinki University Hospital. Based on these answers and predictive algorithms for anxiety and depression, they were guided onto one or several digital intervention paths. Patients under 56 years of age were guided onto a nutrition path, those who exercised less than the current guideline recommendations onto an exercise path, and those at risk of mental health deterioration onto an empowerment path. Information on compliance was collected at 3 months on the amount of exercise and quality of life using EORTC-C30 scale, anxiety and depression using HADS scale at baseline and 12 months, and log-in information at 3 and 12 months.
Thirty-two patients followed the empowerment path, 43 the nutrition path, and 75 the exercise path. On a scale of 1-5, most of the participants (mean = 3.4; SD 0.815) found the interventions helpful and would have recommended testing and supportive interventions to their peers (mean = 3.70; SD 0.961). During the 10-week intervention period, the mean number of log-ins to the empowerment path was 3.69 (SD = 4.24); the nutrition path, 4.32 (SD = 2.891); and the exercise path, 8.33 (SD = 6.293). The higher number of log-ins to the empowerment (rho = 0.531, =0.008, and = 24) and exercise paths (rho = 0.330, =0.01, and = 59) was related to better global quality of life at one year. The number of log-ins correlated to the weekly amount of exercise in the exercise path (cc 0.740, value <0.001, and = 20).
Patients' attitudes towards the interventions were positive, but they used them far less than was recommended. A randomized trial would be needed to test the effect of interventions on patients' QoL and mental health.
尽管早期乳腺癌患者预后良好，但他们仍面临生活质量下降和心理健康方面的问题。需要针对这些问题的可改变因素提供易于获得的干预措施。本研究的目的是测试一种针对早期乳腺癌患者的新型数字支持干预平台的应用。97名早期乳腺癌患者在赫尔辛基大学医院接受全身辅助治疗前，回答了有关幸福感、运动和社会人口学因素的问题。根据这些答案以及焦虑和抑郁的预测算法，引导他们走上一条或几条数字干预路径。56岁以下的患者被引导至营养路径，运动少于当前指南建议的患者被引导至运动路径，有心理健康恶化风险的患者被引导至赋权路径。在3个月时收集依从性信息，包括使用EORTC-C30量表评估的运动量和生活质量，在基线和12个月时使用HADS量表评估的焦虑和抑郁，以及在3个月和12个月时的登录信息。
32名患者遵循赋权路径，43名遵循营养路径，75名遵循运动路径。在1-5分的量表上，大多数参与者（平均=3.4；标准差0.815）认为这些干预措施有帮助，并会向同龄人推荐测试和支持性干预措施（平均=3.70；标准差0.961）。在为期10周的干预期内，赋权路径的平均登录次数为3.69（标准差=4.24）；营养路径为4.
