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本文引用的文献

1
The importance of nutritional factors on the road toward multimodal lifestyle interventions for persistent pain.营养因素在迈向持续性疼痛多模式生活方式干预之路上的重要性。
Braz J Phys Ther. 2024 Sep-Oct;28(5):101119. doi: 10.1016/j.bjpt.2024.101119. Epub 2024 Sep 5.
2
Epigenetic Landscapes of Pain: DNA Methylation Dynamics in Chronic Pain.疼痛的表观遗传学景观：慢性疼痛中的 DNA 甲基化动态。
Int J Mol Sci. 2024 Jul 30;25(15):8324. doi: 10.3390/ijms25158324.
3
Exercise therapy and physical activity in the paradigm shift from a tissue- and disease-based pain management approach towards multimodal lifestyle interventions for chronic pain.从基于组织和疾病的疼痛管理方法向慢性疼痛多模式生活方式干预的范式转变中的运动疗法和身体活动。
Braz J Phys Ther. 2024 Jul-Aug;28(4):101101. doi: 10.1016/j.bjpt.2024.101101. Epub 2024 Jul 27.
4
High-Impact Pain Is Associated With Epigenetic Aging Among Middle-Aged and Older Adults: Findings From the Health and Retirement Study.高冲击性疼痛与中年和老年人的表观遗传衰老有关：来自健康与退休研究的结果。
J Gerontol A Biol Sci Med Sci. 2024 Aug 1;79(8). doi: 10.1093/gerona/glae149.
5
The importance of stress in the paradigm shift from a tissue- and disease-based pain management approach towards multimodal lifestyle interventions for chronic pain.压力在从基于组织和疾病的疼痛管理方法向慢性疼痛的多模式生活方式干预的范式转变中的重要性。
Braz J Phys Ther. 2024 Mar-Apr;28(2):101061. doi: 10.1016/j.bjpt.2024.101061. Epub 2024 Apr 6.
6
The importance of sleep in the paradigm shift from a tissue- and disease-based pain management approach towards multimodal lifestyle interventions for chronic pain.在从基于组织和疾病的疼痛管理方法向慢性疼痛的多模式生活方式干预的范式转变中，睡眠的重要性。
Braz J Phys Ther. 2024 Jan-Feb;28(1):100594. doi: 10.1016/j.bjpt.2024.100594. Epub 2024 Feb 13.
7
Personalized Multimodal Lifestyle Intervention as the Best-Evidenced Treatment for Chronic Pain: State-of-the-Art Clinical Perspective.个性化多模式生活方式干预作为慢性疼痛最有循证依据的治疗方法：最新临床视角
J Clin Med. 2024 Jan 23;13(3):644. doi: 10.3390/jcm13030644.
8
Striving for better outcomes of treating chronic pain: integrating behavioural change strategies before, during, and after modern pain science education.追求慢性疼痛治疗的更好效果：在现代疼痛科学教育之前、期间和之后整合行为改变策略。
Braz J Phys Ther. 2023 Nov-Dec;27(6):100578. doi: 10.1016/j.bjpt.2023.100578. Epub 2023 Dec 8.
9
A paradigm shift from a tissue- and disease-based approach towards multimodal lifestyle interventions for chronic pain: 5 steps to guide clinical reasoning.从基于组织和疾病的方法向慢性疼痛多模式生活方式干预的范式转变：指导临床推理的5个步骤。
Braz J Phys Ther. 2023 Sep-Oct;27(5):100556. doi: 10.1016/j.bjpt.2023.100556. Epub 2023 Nov 7.
10
A DNA methylation signature in the stress driver gene Fkbp5 indicates a neuropathic component in chronic pain.应激驱动基因 FKBP5 中的 DNA 甲基化特征表明慢性疼痛存在神经病理性成分。
Clin Epigenetics. 2023 Sep 30;15(1):155. doi: 10.1186/s13148-023-01569-8.

Epigenetics as the molecular substrate of multimodal lifestyle approaches for patients with persistent pain.

作者信息

Polli Andrea, Nijs Jo, Thienpont Bernard

机构信息

Pain in Motion (PiM) international research group, Department of Physiotherapy, Human Physiology and Anatomy, Faculty of Rehabilitation Sciences & Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium; Department of Public Health and Primary Care, Centre for Environment & Health, KU Leuven, Leuven, Belgium; Flanders Research Foundation - FWO, Belgium.

Pain in Motion (PiM) international research group, Department of Physiotherapy, Human Physiology and Anatomy, Faculty of Rehabilitation Sciences & Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium; Department of Physical Medicine and Physiotherapy, University Hospital Brussels, Brussels, Belgium; Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.

出版信息

Braz J Phys Ther. 2025 Jan-Feb;29(1):101170. doi: 10.1016/j.bjpt.2024.101170. Epub 2024 Dec 31.

DOI:10.1016/j.bjpt.2024.101170
PMID:39742735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11751397/
Abstract
摘要