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本文引用的文献

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Factors driving the inter-individual variability in the metabolism and bioavailability of (poly)phenolic metabolites: A systematic review of human studies.影响（多）酚类代谢物代谢和生物利用度个体间变异性的因素：系统综述人类研究。
Redox Biol. 2024 May;71:103095. doi: 10.1016/j.redox.2024.103095. Epub 2024 Feb 20.
2
(Poly)phenolic compounds and gut microbiome: new opportunities for personalized nutrition.（多）酚类化合物与肠道微生物群：个性化营养的新机遇
Microbiome Res Rep. 2022 Apr 27;1(3):16. doi: 10.20517/mrr.2022.06. eCollection 2022.
3
Optimizing clinical nutrition research: the role of adaptive and pragmatic trials.优化临床营养研究：适应性和实用试验的作用。
Eur J Clin Nutr. 2023 Dec;77(12):1130-1142. doi: 10.1038/s41430-023-01330-7. Epub 2023 Sep 15.
4
Assessing Variability in Vascular Response to Cocoa With Personal Devices: A Series of Double-Blind Randomized Crossover n-of-1 Trials.使用个人设备评估血管对可可反应的变异性：一系列双盲随机交叉单病例试验。
Front Nutr. 2022 Jun 13;9:886597. doi: 10.3389/fnut.2022.886597. eCollection 2022.
5
Gut microbiota as a driver of the interindividual variability of cardiometabolic effects from tea polyphenols.肠道微生物群作为茶多酚对心脏代谢影响个体间差异的驱动因素。
Crit Rev Food Sci Nutr. 2023;63(11):1500-1526. doi: 10.1080/10408398.2021.1965536. Epub 2021 Sep 13.
6
Dietary Flavonoids and Cardiovascular Disease: A Comprehensive Dose-Response Meta-Analysis.饮食类黄酮与心血管疾病：一项综合剂量反应荟萃分析。
Mol Nutr Food Res. 2021 Mar;65(6):e2001019. doi: 10.1002/mnfr.202001019. Epub 2021 Feb 25.
7
Why interindividual variation in response to consumption of plant food bioactives matters for future personalised nutrition.为什么植物食物生物活性成分摄入反应的个体间差异对未来的个性化营养很重要。
Proc Nutr Soc. 2020 May;79(2):225-235. doi: 10.1017/S0029665120000014. Epub 2020 Feb 4.
8
Polyphenols in human nutrition: from the antioxidant capacity to the beneficial effects on cardiometabolic health and related inter-individual variability - an overview and perspective.多酚在人类营养中的作用：从抗氧化能力到对心血管代谢健康的有益影响及相关个体间变异性——综述与展望。
Br J Nutr. 2020 Feb 14;123(3):241-254. doi: 10.1017/S0007114519002733. Epub 2019 Oct 29.
9
Future prospects for dissecting inter-individual variability in the absorption, distribution and elimination of plant bioactives of relevance for cardiometabolic endpoints.未来展望：剖析与心脏代谢终点相关的植物生物活性在吸收、分布和消除方面的个体间变异性。
Eur J Nutr. 2019 Nov;58(Suppl 2):21-36. doi: 10.1007/s00394-019-02095-1. Epub 2019 Oct 23.
10
Factors influencing the cardiometabolic response to (poly)phenols and phytosterols: a review of the COST Action POSITIVe activities.影响（多）酚类物质和植物固醇对心血管代谢反应的因素：COST 行动 POSITIVe 活动综述。
Eur J Nutr. 2019 Nov;58(Suppl 2):37-47. doi: 10.1007/s00394-019-02066-6. Epub 2019 Sep 6.

How to better consider and understand interindividual variability in response to polyphenols in clinical trials.

作者信息

Morand Christine

机构信息

Université Clermont Auvergne, INRAE, UNH, Clermont-Ferrand, France.

出版信息

Front Nutr. 2024 Dec 18;11:1522516. doi: 10.3389/fnut.2024.1522516. eCollection 2024.

DOI:10.3389/fnut.2024.1522516
PMID:39744245
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11688241/
Abstract
摘要