Gonedes Andrew J, Boccio Eric
Emergency Medicine, Memorial Healthcare System, Hollywood, USA.
Cureus. 2024 Dec 1;16(12):e74936. doi: 10.7759/cureus.74936. eCollection 2024 Dec.
A six-year-old boy presented to the pediatric emergency department following an accidental ingestion of a synthetic cannabinoid. The child ingested an edible product containing tetrahydrocannabinol (THC) and presented with lethargy, altered mental status, and increased muscle tone. The airway was protected, and the patient was breathing spontaneously. Initial assessment included a thorough history provided by the caregivers, which confirmed ingestion of cannabinoid gummies approximately two hours prior to presentation. An electrocardiogram demonstrated sinus tachycardia with a prolonged QTc. Toxicology screening was presumed positive for cannabinoids. Therapeutic management focused on supportive care. The patient was admitted to the hospital and discharged on hospital day two with no neurologic sequelae. The caregivers were provided with expectant management and counseled regarding safe storage and use of cannabis and cannabis-derived products. This case report discusses the growing incidence of cannabis exposure in the pediatric population while highlighting the biochemistry, clinical presentation, and therapeutic management of accidental ingestion of synthetic cannabinoids.
一名六岁男童在意外摄入合成大麻素后被送往儿科急诊科。该儿童摄入了一种含四氢大麻酚（THC）的可食用产品，出现嗜睡、精神状态改变和肌张力增加。气道得到保护，患者自主呼吸。初始评估包括护理人员提供的详细病史，证实该儿童在就诊前约两小时摄入了大麻软糖。心电图显示窦性心动过速，QTc间期延长。毒理学筛查推测大麻素呈阳性。治疗管理重点在于支持性护理。患者入院，在住院第二天出院，无神经后遗症。向护理人员提供了预期管理，并就大麻及大麻衍生产品的安全储存和使用进行了咨询。本病例报告讨论了儿科人群中大麻暴露发生率的上升，同时强调了意外摄入合成大麻素的生物化学、临床表现及治疗管理。
