Liu Zonglin, Yao Zhenwei, Yang Haibo, Wu Shiman, Tang Zhongmin
Department of Cardiology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, 200072, China.
Department of Radiology, Huashan Hospital, Fudan University, 200040, Shanghai, China.
Nanoscale. 2025 Feb 13;17(7):3688-3697. doi: 10.1039/d4nr04469j.
The dual role of reactive oxygen species (ROS) in various liver diseases leads to the potential of nanomaterials in addressing challenges related to liver conditions. Considering the pivotal role of ROS in liver disease progression, the design and application of nanomaterials need to align with distinct disease characteristics and the unique liver microenvironment. By reviewing the interaction between nanomaterials and ROS in liver diseases and their potential applications in liver disease treatment, this work discusses the multifaceted properties of nanomaterials and their high specificity and prospects in liver disease treatments.
活性氧（ROS）在各种肝脏疾病中的双重作用，使得纳米材料在应对肝脏疾病相关挑战方面具有潜力。考虑到ROS在肝脏疾病进展中的关键作用，纳米材料的设计和应用需要与不同的疾病特征以及独特的肝脏微环境相匹配。通过综述纳米材料与肝脏疾病中ROS的相互作用及其在肝脏疾病治疗中的潜在应用，本文探讨了纳米材料的多方面特性及其在肝脏疾病治疗中的高特异性和前景。
