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Reply to Lockhart et al.: Advancing the understanding of sex differences in functional brain organization with innovative AI tools.

作者信息

Ryali Srikanth, Zhang Yuan, Supekar Kaustubh, Menon Vinod

机构信息

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA 94305.

Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305.

出版信息

Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2419736121. doi: 10.1073/pnas.2419736121. Epub 2025 Jan 2.

DOI:10.1073/pnas.2419736121
PMID:39746007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11745327/
Abstract
摘要

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本文引用的文献

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Not so binary or generalizable: Brain sex differences with artificial neural networks.并非如此二元或可一概而论：人工神经网络与大脑性别差异
Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2411917121. doi: 10.1073/pnas.2411917121. Epub 2025 Jan 2.
2
Functional brain networks are associated with both sex and gender in children.功能性脑网络与儿童的性别有关。
Sci Adv. 2024 Jul 12;10(28):eadn4202. doi: 10.1126/sciadv.adn4202.
3
Male-female comparisons are powerful in biomedical research - don't abandon them.在生物医学研究中，男女对比作用显著——不要摒弃它们。
Nature. 2024 May;629(8010):37-40. doi: 10.1038/d41586-024-01205-2.
4
Why it's essential to study sex and gender, even as tensions rise.为何即便紧张局势加剧，研究性与性别仍至关重要。
Nature. 2024 May;629(8010):7-8. doi: 10.1038/d41586-024-01207-0.
5
Deep learning models reveal replicable, generalizable, and behaviorally relevant sex differences in human functional brain organization.深度学习模型揭示了人类功能大脑组织中可复制、可推广且与行为相关的性别差异。
Proc Natl Acad Sci U S A. 2024 Feb 27;121(9):e2310012121. doi: 10.1073/pnas.2310012121. Epub 2024 Feb 20.
6
Sex differences in the functional topography of association networks in youth.青少年大脑关联网络功能拓扑的性别差异。
Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2110416119. doi: 10.1073/pnas.2110416119. Epub 2022 Aug 8.
7
Robust, Generalizable, and Interpretable Artificial Intelligence-Derived Brain Fingerprints of Autism and Social Communication Symptom Severity.自闭症和社交沟通症状严重程度的稳健、可推广和可解释的人工智能衍生脑指纹。
Biol Psychiatry. 2022 Oct 15;92(8):643-653. doi: 10.1016/j.biopsych.2022.02.005. Epub 2022 Feb 16.
8
Deep learning identifies robust gender differences in functional brain organization and their dissociable links to clinical symptoms in autism.深度学习识别出功能性脑组织结构中显著的性别差异及其与自闭症临床症状的可分离联系。
Br J Psychiatry. 2022 Apr;220(4):202-209. doi: 10.1192/bjp.2022.13. Epub 2022 Feb 15.
9
Deep learning for sex classification in resting-state and task functional brain networks from the UK Biobank.基于英国生物库静息态和任务功能脑网络的深度学习进行性别分类。
Neuroimage. 2021 Nov 1;241:118409. doi: 10.1016/j.neuroimage.2021.118409. Epub 2021 Jul 20.
10
Sex Classification by Resting State Brain Connectivity.基于静息态脑连接的性别分类。
Cereb Cortex. 2020 Mar 21;30(2):824-835. doi: 10.1093/cercor/bhz129.