盲袢综合征、维生素E吸收不良与脊髓小脑变性。

Blind loop syndrome, vitamin E malabsorption, and spinocerebellar degeneration.

作者信息

Brin M F, Fetell M R, Green P H, Kayden H J, Hays A P, Behrens M M, Baker H

出版信息

Neurology. 1985 Mar;35(3):338-42. doi: 10.1212/wnl.35.3.338.

DOI:10.1212/wnl.35.3.338

Abstract

A 72-year-old man had severe malabsorption, progressive retinopathy, and spinocerebellar degeneration 32 years after gastric surgery, blind loop formation, and intestinal bacterial overgrowth. Clinical and pathologic features were typical of vitamin E deficiency; vitamin E was nearly undetectable in serum and profoundly low in adipose tissue. Vitamin E blood levels initially improved on treatment with antibiotics; after additional vitamin E supplementation, there was clinical improvement.

摘要

一名72岁男性在接受胃手术后32年出现严重吸收不良、进行性视网膜病变和脊髓小脑变性，伴有盲袢形成和肠道细菌过度生长。临床和病理特征符合维生素E缺乏症；血清中维生素E几乎检测不到，脂肪组织中含量极低。使用抗生素治疗后，维生素E血水平最初有所改善；额外补充维生素E后，临床症状有所改善。