South Annabelle, Terré Torras Berta, Rush Hannah, Goodman Anna, Love Sharon
MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, 90 High Holborn, London, WC1V 6LJ, UK.
Trials. 2025 Jan 3;26(1):3. doi: 10.1186/s13063-024-08681-x.
Late-phase clinical trials and systematic reviews find results that have the potential to improve health outcomes for people. However, there are often delays in these results influencing clinical practice. We developed a knowledge transfer and exchange strategy to support research teams, aiming to identify activities along the research process to maximise and accelerate the research impact.
The strategy has five strands of activity across the life-course of our research: 1. Partnerships with external stakeholders (including patient and public involvement, charities, policymakers, healthcare professionals, professional bodies, regulators and industry) 2. Communication (including the development of research impact strategies and use of communication tools and channels) 3. Maximising the scientific value of our studies (including open access, data and sample sharing, and incorporating multi-disciplinary components within studies) 4. Strengthening capacity (including building internal and partner capacity to communicate effectively, and strengthening the capacity of external stakeholders to understand and apply our research). 5. Learning and sharing (evaluating the impact of research, sharing lessons learnt internally and externally) The strategy has helped trial teams think systematically about impact and was easy to use.
Our strategy helps researchers systematically identify activities which may improve the usefulness and uptake of their study results. While developed in a single trials unit, we think it may be of use to others.
晚期临床试验和系统评价得出的结果有可能改善人们的健康状况。然而，这些结果影响临床实践往往存在延迟。我们制定了一项知识转移与交流战略来支持研究团队，旨在确定研究过程中的各项活动，以最大化并加速研究影响力。
该战略在我们研究的整个生命周期中有五个活动方向：1. 与外部利益相关者建立伙伴关系（包括患者和公众参与、慈善机构、政策制定者、医疗保健专业人员、专业团体、监管机构和行业）2. 沟通（包括制定研究影响力战略以及使用沟通工具和渠道）3. 最大化我们研究的科学价值（包括开放获取、数据和样本共享，以及在研究中纳入多学科组成部分）4. 加强能力（包括培养内部和合作伙伴有效沟通的能力，以及增强外部利益相关者理解和应用我们研究的能力）5. 学习与分享（评估研究的影响，在内部和外部分享经验教训）该战略有助于试验团队系统地思考影响力，并且易于使用。
我们的战略有助于研究人员系统地识别可能提高其研究结果实用性和采用率的活动。虽然是在单个试验单位制定的，但我们认为它可能对其他单位有用。
