Singh Jyoti, Saxena Etika, Chaudhary Anjali Raj, Kaur Mandeep, Salotra Molly, Rasane Prasad, Kaur Sawinder, Ercisli Sezai, Durul Melekber Sulusoglu, Bozhuyuk Mehmet Ramazan, Urusan Ahmet Hakan, Ullah Riaz
Department of Food Technology and Nutrition, Lovely Professional University, Phagwara, Punjab, 144411, India.
Department of Horticulture, Faculty of Agriculture, Ataturk University, 25240, Erzurum, Turkiye.
Heliyon. 2024 Dec 7;11(1):e40948. doi: 10.1016/j.heliyon.2024.e40948. eCollection 2025 Jan 15.
In Ayurvedic texts, Giloy ( have been known as the most potent and important medicinal product. Giloy leaves have been used for centuries to cure various ailments and diseases in the human body. This review highlights that giloy leaves have immunomodulatory properties and can be used to develop functional food products. The current review focuses on the phytochemical composition of giloy leaves, and the mechanism for their immunomodulatory action highlighting specific pathways including NF-kB pathway and interleukin modulation. Giloy leaves possess antioxidant activity and induce apoptosis of cells in the immune response. Studies have shown the potential of incorporating giloy leaves into a wide range of value-added products, such as beverages, biscuits, and herbal formulations, to bridge traditional knowledge with modern functional food production. A comparison of traditional and modern giloy-based products demonstrates their benefits and drawbacks, showing that traditional techniques can be combined with modern scientific developments to improve medicinal efficacy. Although giloy leaves-based products show promising potential, further research is necessary to ascertain their effectiveness.
在阿育吠陀文献中，吉尔罗伊（已被认为是最具效力和重要的药用产品。吉尔罗伊叶已被用于治疗人体各种疾病达数百年之久。本综述强调吉尔罗伊叶具有免疫调节特性，可用于开发功能性食品。当前综述聚焦于吉尔罗伊叶的植物化学成分及其免疫调节作用机制，突出了包括NF-κB途径和白细胞介素调节在内的特定途径。吉尔罗伊叶具有抗氧化活性，并在免疫反应中诱导细胞凋亡。研究表明，将吉尔罗伊叶纳入多种增值产品，如饮料、饼干和草药配方的潜力，以将传统知识与现代功能性食品生产相联系。对传统和现代吉尔罗伊基产品的比较展示了它们的优缺点，表明传统技术可与现代科学发展相结合以提高药用功效。尽管基于吉尔罗伊叶的产品显示出有前景的潜力，但仍需进一步研究以确定其有效性。
