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用于检测乳腺癌模型异常的多频电阻抗断层成像(Mf-EIT)。

Multifrequency electrical impedance tomography (Mf-EIT) for the detection of breast cancer phantom anomalies.

作者信息

Ariwanto Bayu, Ain Khusnul, Rulaningtyas Riries, Ukhrowiyah Nuril, Aisya Rohadatul, Basori Ahmad Hoirul, Mansur Andi Besse Fidausiah

机构信息

Magister of Biomedical Engineering, Faculty of Science and Technology, Airlangga University, Surabaya 60115, Indonesia.

Faculty of Computing and Information Technology in Rabigh, King Abdulaziz University, Rabigh 21911, Saudi Arabia.

出版信息

MethodsX. 2024 Dec 6;14:103087. doi: 10.1016/j.mex.2024.103087. eCollection 2025 Jun.

Abstract

Breast cancer is the most commonly diagnosed neoplasm and one of the most widespread cancers among women. The research advanced the Mf-EIT hardware through analogue discovery, component assessment, hardware integration, software creation, and data reconstruction utilizing Gauss-Newton and GREIT approaches. The breast cancer phantom consisted of a gelatin and sodium chloride solution. The position and number of anomalies in the reconstructed image correspond with the phantom. Anomalies in the reconstructed image are illustrated in red, indicating that they exhibit higher conductivity than their environment. The smallest percentage difference in conductivity between the reconstructed image of the cancer abnormality and the phantom is 0.18 %, recorded at a current of 0.35 mA and a frequency of 150 kHz. The smallest percentage difference in size between cancer abnormalities 1 and 2 in the reconstructed image and the phantom is 0.14 %, observed at a current of 0.22 mA and a frequency of 80 kHz. In brief,•This study proposes an innovative Electrical Impedance Tomography (EIT)•The designed and built the Mf-EIT hardware based on data reconstruction using Gauss-Newton and GREIT•The Electrical Impedance Tomography designed to detect the anomalies in the reconstructed image of Breast Cancer.

摘要

乳腺癌是最常被诊断出的肿瘤,也是女性中最常见的癌症之一。该研究通过模拟发现、组件评估、硬件集成、软件创建以及利用高斯-牛顿法和GREIT方法进行数据重建,改进了Mf-EIT硬件。乳腺癌体模由明胶和氯化钠溶液组成。重建图像中异常的位置和数量与体模一致。重建图像中的异常用红色表示,表明它们的电导率高于周围环境。在0.35 mA的电流和150 kHz的频率下,癌症异常重建图像与体模之间电导率的最小百分比差异为0.18%。在0.22 mA的电流和80 kHz的频率下,重建图像中癌症异常1和2与体模之间尺寸的最小百分比差异为0.14%。简而言之,•本研究提出了一种创新的电阻抗断层成像(EIT)•基于使用高斯-牛顿法和GREIT的数据重建设计并构建了Mf-EIT硬件•设计的电阻抗断层成像用于检测乳腺癌重建图像中的异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77fa/11699602/b0225d182677/ga1.jpg

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