Ghaffari Sarghein Mehdi, Abbasalizad Farhangi Mahdieh, Nikrad Negin
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Community Nutrition, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, Iran.
Nutr Metab Insights. 2025 Jan 2;18:11786388241309847. doi: 10.1177/11786388241309847. eCollection 2025.
Metabolic syndrome (MetS) is defined as the existence of metabolic profile risk factors and impaired glycemic status such as dysglycemia, hyperinsulinemia, insulin resistance (IR), dyslipidemia, and hypertension. Several studies demonstrated that a diet that promotes proper nutritional intake; plays a critical role in the prevention and control of MetS. Our goal for conducting this cross-sectional study was to investigate any potential relationships between the nutrient adequacy ratio (NAR) and cardiometabolic risk variables within obese individuals. individuals.
In the present cross-sectional study, 338 seemingly healthy participants who were overweight or obese were enrolled. The assessment of dietary consumption was conducted through a validated questionnaire comprising 168 items Then NAR was calculated for all ten vitamins and six minerals. Biochemical variables are measured by the method of enzyme-linked immunosorbent assay (ELISA). Also, LDL-C (low-density lipoprotein-cholesterol), QUICKI (quantitative insulin-sensitivity check index), and HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) were calculated using the suggested formulas.
Subjects in the upper NAR tertiles exhibited a significantly higher percentage of fat-free mass ( = .002), appetite ( = .002), and basal metabolic rate (BMR) ( = .002). In addition, Participants in the upper tertiles of NAR consumed a greater amount of energy and all vitamins and minerals included in NAR and meat, fish and poultry (MFP) ( < .001) as well as cholesterol, monounsaturated fatty acid (MUFA), and polyunsaturated fatty acid (PUFA) ( < .05). Furthermore, no association was shown between NAR and metabolic profile and glycemic status.
According to our findings, a higher nutrient adequacy ratio (NAR) was associated with higher fat-free mass but no significant link between NAR and metabolic profile risk factors was observed.
代谢综合征（MetS）被定义为存在代谢谱风险因素以及血糖状态受损，如血糖异常、高胰岛素血症、胰岛素抵抗（IR）、血脂异常和高血压。多项研究表明，促进适当营养摄入的饮食在代谢综合征的预防和控制中起着关键作用。我们开展这项横断面研究的目的是调查肥胖个体中营养充足率（NAR）与心脏代谢风险变量之间的潜在关系。
在本横断面研究中，招募了338名看似健康的超重或肥胖参与者。通过一份包含168个条目的有效问卷对饮食消费进行评估，然后计算所有十种维生素和六种矿物质的NAR。生化变量采用酶联免疫吸附测定（ELISA）法进行测量。此外，使用建议公式计算低密度脂蛋白胆固醇（LDL-C）、定量胰岛素敏感性检查指数（QUICKI）和胰岛素抵抗稳态模型评估（HOMA-IR）。
处于NAR三分位数较高组的受试者无脂肪体重百分比（P = 0.002）、食欲（P = 0.002）和基础代谢率（BMR）（P = 0.002）显著更高。此外，NAR三分位数较高组的参与者消耗了更多能量以及NAR中包含的所有维生素和矿物质、肉、鱼和家禽（MFP）（P < .001）以及胆固醇、单不饱和脂肪酸（MUFA）和多不饱和脂肪酸（PUFA）（P < .05）。此外，未发现NAR与代谢谱和血糖状态之间存在关联。
根据我们的数据，较高的营养充足率（NAR）与较高的无脂肪体重相关，但未观察到NAR与代谢谱风险因素之间存在显著关联。
