Heredia Luis, Murcia-Mejía Mauricio, Torrente Margarita
Rovira i Virgili University, Department of Psychology, Research Center for Behavior Assessment (CRAMC), Tarragona, Spain.
Rovira i Virgili University, Center for Environmental, Food and Toxicological Technology (TECNATOX), Laboratory of Toxicology and Environmental Health (LTSM), School of Medicine, Reus, Spain.
Data Brief. 2024 Dec 6;58:111197. doi: 10.1016/j.dib.2024.111197. eCollection 2025 Feb.
This article presents data collected from 15 patients diagnosed with small-cell lung cancer who received prophylactic cranial irradiation (PCI), with or without hippocampal avoidance. Patient assessments included two specific questionnaires related to quality of life and an extensive neurocognitive evaluation. The evaluation covered various domains: verbal short-term memory, working memory, visuoconstructive abilities, visuospatial memory, semantic memory, verbal fluency, cognitive flexibility, inhibitory control, selective and divided attention, and processing speed. Assessments were conducted prior to PCI and at 3, 6, 12, and 24 months post-treatment. Despite the limited sample size due to challenges in patient recruitment and comprehensive follow-up, the data presented may help to identify the neuropsychological domains most affected in this population and can be useful in the design of future larger-scale studies. At present, there is limited information regarding the neuropsychological profiles of these patients and most studies focus on only one or two neuropsychological domains, typically emphasizing working memory assessments.
本文介绍了从15例被诊断为小细胞肺癌且接受了预防性颅脑照射（PCI）（无论是否避开海马体）的患者中收集的数据。患者评估包括两份与生活质量相关的特定问卷以及一次全面的神经认知评估。该评估涵盖多个领域：言语短期记忆、工作记忆、视觉建构能力、视觉空间记忆、语义记忆、言语流畅性、认知灵活性、抑制控制、选择性和分散性注意力以及处理速度。评估在PCI之前以及治疗后3个月、6个月、12个月和24个月进行。尽管由于患者招募和全面随访方面的挑战导致样本量有限，但所呈现的数据可能有助于确定该人群中受影响最大的神经心理学领域，并且对未来大规模研究的设计可能有用。目前，关于这些患者的神经心理学概况的信息有限，大多数研究仅关注一两个神经心理学领域，通常侧重于工作记忆评估。
