Boonrat Kanitsorn, Jaroenkunpanit Pinyada, Wounchoum Phairote, Jantarachote Vasan, Chetpattananondh Pakamas, Chetpattananondh Kanadit
Department of Electrical and Biomedical Engineering, Faculty of Engineering, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
Department of Chemical Engineering, Faculty of Engineering, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.
ACS Omega. 2024 Dec 17;9(52):51515-51524. doi: 10.1021/acsomega.4c08811. eCollection 2024 Dec 31.
This feasibility study presents a novel noncontact method for differentiating standard cannabidiol (CBD) concentrations using optimized interdigital electrodes. The electrode design, with a 100 mm sensing area on a 64 mm × 77 mm FR-4 substrate, was improved through finite element analysis. Methanol-CBD solutions (25-1000 ppm) in 2 mL glass vials were analyzed using a vector network analyzer connected via a high-frequency SMA connector, focusing on scattering parameter (S-parameter) changes. The method demonstrated high effectiveness in CBD concentration differentiation, achieving a concentration resolution of 145 MHz/50 ppm based on resonant frequency shift, with an error of 0.17% of the reading, and 0.5 dB/50 ppm using S amplitude measurement. The proposed method offers a promising, linear, and precise technique for noncontact CBD standard analysis, with potential applications in future research. In addition, impedance measurements can be applied to enhance concentration differentiation further.
本可行性研究提出了一种使用优化叉指电极区分标准大麻二酚（CBD）浓度的新型非接触方法。通过有限元分析改进了电极设计，该电极在64 mm×77 mm的FR-4基板上具有100 mm的传感面积。使用通过高频SMA连接器连接的矢量网络分析仪分析了2 mL玻璃瓶中的甲醇-CBD溶液（25-1000 ppm），重点关注散射参数（S参数）的变化。该方法在CBD浓度区分方面显示出高效性，基于共振频率偏移实现了145 MHz/50 ppm的浓度分辨率，读数误差为0.17%，使用S幅度测量时为0.5 dB/50 ppm。所提出的方法为非接触式CBD标准分析提供了一种有前景、线性且精确的技术，在未来研究中具有潜在应用。此外，阻抗测量可用于进一步提高浓度区分能力。
