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使用大麻二酚的原因:一项针对大麻二酚使用者的横断面研究,重点关注自我感知的压力、焦虑和睡眠问题。

Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems.

作者信息

Moltke Julie, Hindocha Chandni

机构信息

Clinic Horsted, Chronic Pain Clinic, Farvegade 2, 1463, Copenhagen, Denmark.

Clinical Psychopharmacology Unit, Department of Clinical, Educational & Health Psychology, University College London, London, UK.

出版信息

J Cannabis Res. 2021 Feb 18;3(1):5. doi: 10.1186/s42238-021-00061-5.

Abstract

BACKGROUND

Public and medical interest in cannabidiol (CBD) has been rising, and CBD is now available from various sources. Research into the effects of low-dose CBD on outcomes like stress, anxiety, and sleep problems have been scarce, so we conducted an online survey of CBD users to better understand patterns of use, dose, and self-perceived effects of CBD.

METHODS

The sample consisted of 387 current or past-CBD users who answered a 20-question online survey. The survey was sent out to CBD users through email databases and social media. Participants reported basic demographics, CBD use patterns, reasons for use, and effects on anxiety, sleep, and stress.

RESULTS

The sample (N = 387) consisted of 61.2% females, mostly between 25 and 54 years old (72.2%) and primarily based in the UK (77.4%). The top 4 reasons for using CBD were self-perceived anxiety (42.6%), sleep problems (42.5%), stress (37%), and general health and wellbeing (37%). Fifty-four per cent reported using less than 50 mg CBD daily, and 72.6% used CBD sublingually. Adjusted logistic models show females had lower odds than males of using CBD for general health and wellbeing [OR 0.45, 95% CI 0.30-0.72] and post-workout muscle-soreness [OR 0.46, 95%CI 0.24-0.91] but had higher odds of using CBD for self-perceived anxiety [OR 1.60, 95% CI 0.02-2.49] and insomnia [OR 1.87, 95% CI 1.13-3.11]. Older individuals had lower odds of using CBD for general health and wellbeing, stress, post-workout sore muscles, anxiety, skin conditions, focusing, and sleep but had higher odds of using CBD for pain. Respondents reported that CBD use was effective for stress, sleep problems, and anxiety in those who used the drug for those conditions.

CONCLUSION

This survey indicated that CBD users take the drug to manage self-perceived anxiety, stress, sleep, and other symptoms, often in low doses, and these patterns vary by demographic characteristics. Further research is required to understand how low doses, representative of the general user, might impact mental health symptoms like stress, anxiety, and sleep problems.

摘要

背景

公众和医学界对大麻二酚(CBD)的兴趣不断上升,目前可从多种来源获取CBD。关于低剂量CBD对压力、焦虑和睡眠问题等结果影响的研究较少,因此我们对CBD使用者进行了一项在线调查,以更好地了解其使用模式、剂量和自我感知的效果。

方法

样本包括387名当前或过去的CBD使用者,他们回答了一项包含20个问题的在线调查。该调查通过电子邮件数据库和社交媒体发送给CBD使用者。参与者报告了基本人口统计学信息、CBD使用模式、使用原因以及对焦虑、睡眠和压力的影响。

结果

样本(N = 387)中61.2%为女性,大多年龄在25至54岁之间(72.2%),主要来自英国(77.4%)。使用CBD的前四大原因是自我感知的焦虑(42.6%)、睡眠问题(42.5%)、压力(37%)以及总体健康和幸福感(37%)。54%的人报告每天使用少于50毫克的CBD,72.6%的人通过舌下含服使用CBD。调整后的逻辑模型显示,女性因总体健康和幸福感使用CBD的几率低于男性[比值比(OR)0.45,95%置信区间(CI)0.30 - 0.72],因运动后肌肉酸痛使用CBD的几率也低于男性[OR 0.46,95%CI 0.24 - 0.91],但因自我感知的焦虑使用CBD的几率高于男性[OR 1.60,95%CI 0.02 - 2.49],因失眠使用CBD的几率高于男性[OR 1.87,95%CI 1.13 - 3.11]。年龄较大的个体因总体健康和幸福感、压力、运动后肌肉酸痛、焦虑、皮肤状况、注意力集中和睡眠使用CBD的几率较低,但因疼痛使用CBD的几率较高。受访者报告称,对于因这些状况使用该药物的人来说,CBD对压力、睡眠问题和焦虑有效。

结论

这项调查表明,CBD使用者服用该药物来管理自我感知的焦虑、压力、睡眠和其他症状,通常剂量较低,且这些模式因人口统计学特征而异。需要进一步研究以了解代表普通使用者的低剂量CBD可能如何影响压力、焦虑和睡眠问题等心理健康症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dec/7893882/62d08ee4fa0c/42238_2021_61_Fig1_HTML.jpg

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