Ulmer W
Strahlentherapie. 1985 Mar;161(3):177-85.
In many problems of modern radiotherapy such as multifractionation, interstitial and intracavitary therapy with implanats the NSD-formula is hardly applicable. Serious difficulties arise, when this formula is used for an estimation of late responses of tissues, because it mainly appreciates acute effects. On the basis of the linear-quadratic survival model S = exp (-alpha D - beta D2) the TDF-problem is investigated with the help of kinetic principles.
在现代放射治疗的许多问题中，如多分割放疗、组织间和腔内植入治疗，NSD公式几乎不适用。当用这个公式来估计组织的晚期反应时，会出现严重困难，因为它主要评估的是急性效应。基于线性二次生存模型S = exp (-αD - βD²)，借助动力学原理研究了TDF问题。
