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牛肉肉质的血清标志物:细胞培养肉生产的潜在培养基补充剂。

Serum markers for beef meat quality: Potential media supplement for cell-cultured meat production.

作者信息

Iram Sana, Akash Amar, Kathera Chandra Sekhar, Park Kye Won, Cho Yoon Shin, Kim Jihoe

机构信息

Department of Medical Biotechnology and Research Institute of Cell Culture, Yeungnam University, Gyeongsan, 38541, Republic of Korea.

Department of Food Science and Biotechnology, Food Clinical Research Center, Sungkyunkwan University, Suwon, 16419, Republic of Korea.

出版信息

Curr Res Food Sci. 2024 Dec 3;10:100943. doi: 10.1016/j.crfs.2024.100943. eCollection 2025.

Abstract

As the global population continues to grow and food demands increase, the food industry faces mounting pressure to develop innovative solutions. Cell-cultured meat involves cultivating cells from live animals through self-renewal methods or scaffolding and presents a promising alternative to traditional meat production by generating nutritionally rich biomass. However, significant research is still needed to overcome challenges such as developing serum-free media, identifying suitable additives to support cell growth, and ensuring the quality of cell-cultured meat closely resembles that of traditional meat. Meat quality, which is influenced by various sensorial factors (color, texture, and taste), tenderness, and nutritional values, is determined by the level of intramuscular fat deposition, which significantly influences both meat yield and quality. This paper offers a concise overview of serum markers used to assess beef quality and yield and potential additives currently used in culture media for cell-cultured meat production. We also proposed the potential of using serum markers as additives in the culture media to enhance production of cell-cultured meat. Overall, this review highlights the significance of cell-cultured meat production as a viable solution to address the challenges posed by increasing food demands.

摘要

随着全球人口持续增长以及食物需求增加,食品行业面临着开发创新解决方案的巨大压力。细胞培养肉涉及通过自我更新方法或支架培养活体动物的细胞,并通过产生营养丰富的生物质,为传统肉类生产提供了一种有前景的替代方案。然而,仍需要大量研究来克服各种挑战,如开发无血清培养基、确定支持细胞生长的合适添加剂以及确保细胞培养肉的质量与传统肉的质量非常相似。肉质受多种感官因素(颜色、质地和味道)、嫩度和营养价值的影响,由肌内脂肪沉积水平决定,而肌内脂肪沉积水平对肉的产量和质量都有显著影响。本文简要概述了用于评估牛肉质量和产量的血清标志物以及目前细胞培养肉生产培养基中使用的潜在添加剂。我们还提出了将血清标志物用作培养基添加剂以提高细胞培养肉产量的可能性。总体而言,本综述强调了细胞培养肉生产作为应对不断增加的食物需求所带来挑战的可行解决方案的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b531/11696856/7082f16b51d9/ga1.jpg

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