Gao Aifang, You Xi, Li Zhao, Liao Chenglong, Yin Ze, Zhang Baojun, Zhang Hongliang
School of Water Resources and Environment, Hebei GEO University, Hebei Province Collaborative Innovation Center for Sustainable Utilization of Water Resources and Optimization of Industrial Structure, Hebei Province Key Laboratory of Sustained Utilization and Development of Water Resources, Hebei Center for Ecological and Environmental Geology Research, Shijiazhuang, 050031, China.
School of Water Resources and Environment, Hebei GEO University, Hebei Province Collaborative Innovation Center for Sustainable Utilization of Water Resources and Optimization of Industrial Structure, Hebei Province Key Laboratory of Sustained Utilization and Development of Water Resources, Hebei Center for Ecological and Environmental Geology Research, Shijiazhuang, 050031, China.
Environ Pollut. 2025 Feb 15;367:125642. doi: 10.1016/j.envpol.2025.125642. Epub 2025 Jan 4.
As the ozone (O) pollution becomes severe in China, it poses a threat to human health. Currently, studies on the impacts of O on different regions and groups are limited. This review systematically summarizes the relationship between O pollution and mortality and morbidity across the nation, regions, and cities in China, with a focus on the regional and group-specific studies. Then, we clarify the overall limitations in the research data, methods, and subjects. In addition, we briefly discuss the mechanisms by which O exposure affects human health, analyzing the effects of O on human health under heatwaves (temperature) condition, multi-pollutant modeling, and future climate scenarios. Finally, we give some suggestions for future research directions. Studies found that increased risks of premature mortality and morbidity of respiratory and cardiovascular diseases are closely associated with high concentration O exposure. Besides, the old and children are sensitive groups, more studies are needed estimate the risk of their health associated with O pollution. Severe O pollution in Northern and Eastern China, has significantly increased premature mortality. O pollution has led to decreased lung function in the elderly in East China, and a higher asthma risk among young people in South China. Comparing with other regions, less research studied the relationship between O pollution and health of local people in Southwest, Central, Northeast, and Northwest Regions. Therefore, it is necessary to enhance research in these regions, with a particular emphasis on the distinctive health consequences of O pollution in these regions. Given the diversity of regions and research groups, comprehensive comparison is crucial for determining the impact of O pollution on human health in China.
随着中国臭氧（O）污染日益严重，它对人类健康构成了威胁。目前，关于臭氧对不同地区和人群影响的研究有限。本综述系统总结了中国全国、各地区和城市臭氧污染与死亡率和发病率之间的关系，重点关注区域和特定人群的研究。然后，我们阐明了研究数据、方法和研究对象方面的总体局限性。此外，我们简要讨论了臭氧暴露影响人类健康的机制，分析了在热浪（温度）条件下、多污染物模型以及未来气候情景下臭氧对人类健康的影响。最后，我们对未来的研究方向提出了一些建议。研究发现，呼吸道和心血管疾病过早死亡和发病风险的增加与高浓度臭氧暴露密切相关。此外，老年人和儿童是敏感人群，需要更多研究来评估他们与臭氧污染相关的健康风险。中国北方和东部的严重臭氧污染显著增加了过早死亡率。臭氧污染导致华东地区老年人肺功能下降，华南地区年轻人哮喘风险更高。与其他地区相比，西南、中部、东北和西北地区关于臭氧污染与当地人群健康关系的研究较少。因此，有必要加强这些地区的研究，尤其要关注这些地区臭氧污染独特的健康后果。鉴于地区和研究人群的多样性，全面比较对于确定臭氧污染对中国人类健康的影响至关重要。
