Ide C, Tohyama K
Acta Anat (Basel). 1985;121(2):110-4. doi: 10.1159/000145952.
The presence of macrophages in the outer bulb region of mouse, monkey and human Pacinian corpuscles was demonstrated by light and electron microscopy. In the normal, nontreated, Pacinian corpuscles, a few particular cells were located in the spaces between lamellae of the outer bulb. These cells contained numerous vesicles and vacuoles, and various cytoplasmic processes. When horseradish peroxidase (HRP) was injected locally or systemically, many HRP-positive cells, which were considered to be similar to the particular cells described above, were found in the outer bulb region of the corpuscles. Electron microscopy revealed that these cells contained HRP in vesicles and vacuoles, suggesting that they were macrophages vigorously taking up exogenous HRP. Macrophages in the Pacinian corpuscles are considered to work as scavengers to keep the inner environment of the corpuscles clear and constant with regard to its macromolecular content.
通过光学显微镜和电子显微镜证实，在小鼠、猴子和人类的环层小体的外球区域存在巨噬细胞。在正常的、未经处理的环层小体中，外球板层之间的间隙中有一些特殊细胞。这些细胞含有大量的小泡和液泡以及各种细胞质突起。当局部或全身注射辣根过氧化物酶（HRP）时，在环层小体的外球区域发现了许多HRP阳性细胞，这些细胞被认为与上述特殊细胞相似。电子显微镜显示，这些细胞的小泡和液泡中含有HRP，这表明它们是积极摄取外源性HRP的巨噬细胞。环层小体中的巨噬细胞被认为起到清除剂的作用，以保持环层小体内部环境在大分子含量方面的清洁和稳定。
