Pre-trained Convolutional Neural Networks Identify Parkinson's Disease from Spectrogram Images of Voice Samples.

Machine learning approaches including deep learning models have shown promising performance in the automatic detection of Parkinson's disease. These approaches rely on different types of data with voice recordings being the most used due to the convenient and non-invasive nature of data acquisition. Our group has successfully developed a novel approach that uses convolutional neural network with transfer learning to analyze spectrogram images of the sustained vowel /a/ to identify people with Parkinson's disease. We tested this approach by collecting a dataset of voice recordings via telephone lines, which have limited bandwidth. This study builds upon our prior results in two major ways: First, we tested the performance of our approach on a larger voice dataset recorded using smartphones with wide bandwidth. Our results show comparable performance between two datasets generated using different recording platforms where we report differences in most important features resulting from the limited bandwidth of telephonic lines. Second, we compared the classification performance achieved using linear-scale and mel-scale spectrogram images and showed a small but statistically significant gain using mel-scale spectrograms. The convolutional neural network with transfer learning approach showed superior performance against conventional machine learning methods that collapse measurements across time to generate feature vectors.