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帕金森病的商业症状监测设备:益处、局限性及趋势

Commercial symptom monitoring devices in Parkinson's disease: benefits, limitations, and trends.

作者信息

Rodríguez-Martín Daniel, Pérez-López Carlos

机构信息

Sense4Care, Cornellà de Llobregat, Spain.

Consorci Sanitari Alt Penedès-Garraf, Vilanova i la Geltrú, Spain.

出版信息

Front Neurol. 2024 Dec 23;15:1470928. doi: 10.3389/fneur.2024.1470928. eCollection 2024.

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder that significantly impacts patients' quality of life. Managing PD requires accurate assessment of motor and non-motor symptoms, often complicated by the subjectivity in symptom reporting and the limited availability of neurologists. To address these challenges, commercial wearable devices have emerged to continuously monitor PD symptoms outside the clinical setting. The main devices include PKG™, Kinesia 360™, Kinesia U™, PDMonitor™, and STAT-ON™. These devices utilize advanced technologies such as accelerometers, gyroscopes, and specific algorithms to provide objective data on motor symptoms like tremors, dyskinesia, and bradykinesia. Despite their potential, the adoption of these devices is limited due to concerns about their accuracy, complexity of use, and lack of independent validation. The correlation between these devices' measurements and traditional clinical observations varies, and patient usability and adherence remain critical areas for improvement. To optimize their utility and improve patient outcomes, it is essential to conduct validation and usability studies with a sufficient number of patients, develop standardized protocols, and ensure integration with hospital information systems.

摘要

帕金森病(PD)是一种神经退行性疾病,会严重影响患者的生活质量。管理帕金森病需要准确评估运动和非运动症状,但症状报告的主观性以及神经科医生数量有限常常使这一过程变得复杂。为应对这些挑战,市面上出现了可穿戴设备,用于在临床环境之外持续监测帕金森病症状。主要设备包括PKG™、Kinesia 360™、Kinesia U™、PDMonitor™和STAT-ON™。这些设备利用加速度计、陀螺仪等先进技术以及特定算法,提供有关震颤、运动障碍和运动迟缓等运动症状的客观数据。尽管这些设备具有潜力,但由于对其准确性、使用复杂性以及缺乏独立验证的担忧,其采用率仍然有限。这些设备的测量结果与传统临床观察之间的相关性各不相同,患者的易用性和依从性仍是亟待改善的关键领域。为了优化其效用并改善患者治疗效果,必须对足够数量的患者进行验证和可用性研究,制定标准化方案,并确保与医院信息系统集成。

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