Rossi Marianna Nicoletta, Cervelli Manuela
Department of Sciences, University of Roma Tre, 00146 Rome, Italy.
Biomolecules. 2024 Dec 9;14(12):1570. doi: 10.3390/biom14121570.
The polyamines putrescine, spermidine, and spermine are polycations ubiquitously present in cells, where they exert pleiotropic functions in cellular mechanisms like proliferation, protein synthesis (through the hypusination of the transcription factor EIF5a), redox balance, autophagy, and different forms of cell death [...].
多胺腐胺、亚精胺和精胺是普遍存在于细胞中的多阳离子，它们在细胞增殖、蛋白质合成（通过转录因子EIF5a的hypusination）、氧化还原平衡、自噬和不同形式的细胞死亡等细胞机制中发挥多效性功能[……]
