多胺代谢与功能：在细胞健康与疾病中的关键作用
Polyamine Metabolism and Functions: Key Roles in Cellular Health and Disease.
作者信息
Rossi Marianna Nicoletta, Cervelli Manuela
机构信息
Department of Sciences, University of Roma Tre, 00146 Rome, Italy.
出版信息
Biomolecules. 2024 Dec 9;14(12):1570. doi: 10.3390/biom14121570.
Abstract
The polyamines putrescine, spermidine, and spermine are polycations ubiquitously present in cells, where they exert pleiotropic functions in cellular mechanisms like proliferation, protein synthesis (through the hypusination of the transcription factor EIF5a), redox balance, autophagy, and different forms of cell death [...].
摘要
多胺腐胺、亚精胺和精胺是普遍存在于细胞中的多阳离子，它们在细胞增殖、蛋白质合成（通过转录因子EIF5a的hypusination）、氧化还原平衡、自噬和不同形式的细胞死亡等细胞机制中发挥多效性功能[……]
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