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合理使用抗生素以牙科伦理原则为基础:研究生和本科牙科学生认知调查

Rational Antibiotic Prescribing Is Underpinned by Dental Ethics Principles: Survey on Postgraduate and Undergraduate Dental Students' Perceptions.

作者信息

Roganović Jelena, Barać Milena

机构信息

Department of Pharmacology in Dentistry, Faculty of Dental Medicine, University of Belgrade, Dr Subotica 1, 11 000 Belgrade, Serbia.

出版信息

Antibiotics (Basel). 2024 May 17;13(5):460. doi: 10.3390/antibiotics13050460.

DOI:10.3390/antibiotics13050460
PMID:38786188
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11118224/
Abstract

BACKGROUND

Dentists bear the burden of responsibility for antimicrobial resistance since antibiotics are the drugs most prescribed by dentists. Often, "inappropriate" antibiotic use is considered as a "gray area" by dentists mainly due to ethical challenges associated with the clinical judgement depending on patients and/or prescribers.

AIM

The study aimed to assess whether and in what way dental ethical principles underpin rational antibiotic use by investigating perceptions of postgraduate and undergraduate dental students without formal knowledge of dental ethics.

METHOD

A cross-sectional anonymous survey comprised nine close-ended questions and was conducted among dental students (n = 125). The investigated practice of appropriate antibiotic prescribing in the survey relied on the respect of three basic principles of ethics: autonomy, non-maleficence, and beneficence.

RESULTS

Results show that dental students exhibit a lack of dental ethics knowledge that results in an inappropriate antibiotic-prescribing practice: prescribing an antibiotic when it is not necessary, without examination, or for indications that are not within the competence of the dentist. Multivariate regression analysis revealed that there was a significant difference between under- and postgraduates.

CONCLUSIONS

Within the pharmacology course, a review of the clinical scenarios which cover both ethical and clinical complexities regarding the appropriate use of antibiotics should be introduced as an educational approach.

摘要

背景

由于抗生素是牙医最常开具的药物,因此牙医肩负着对抗菌素耐药性的责任。通常,牙医将“不适当”的抗生素使用视为一个“灰色地带”,主要是因为这涉及到基于患者和/或开处方者的临床判断所带来的伦理挑战。

目的

本研究旨在通过调查没有牙科伦理方面正规知识的研究生和本科生的看法,评估牙科伦理原则是否以及如何支持合理使用抗生素。

方法

对125名牙科学生进行了一项包含九个封闭式问题的横断面匿名调查。调查中所研究的适当抗生素处方行为依赖于对三项基本伦理原则的遵守:自主性、不伤害原则和有益原则。

结果

结果显示,牙科学生缺乏牙科伦理知识,这导致了不适当的抗生素处方行为:在不必要时、未经检查或超出牙医能力范围的适应症情况下开具抗生素。多变量回归分析显示,本科生和研究生之间存在显著差异。

结论

在药理学课程中,应引入对涵盖抗生素合理使用的伦理和临床复杂性的临床案例的回顾,作为一种教育方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca1/11118224/06f9ba30180b/antibiotics-13-00460-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca1/11118224/748be7389f8c/antibiotics-13-00460-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca1/11118224/ea700c70226a/antibiotics-13-00460-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca1/11118224/06f9ba30180b/antibiotics-13-00460-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca1/11118224/748be7389f8c/antibiotics-13-00460-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca1/11118224/ea700c70226a/antibiotics-13-00460-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ca1/11118224/06f9ba30180b/antibiotics-13-00460-g003.jpg

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Antibiotics (Basel). 2024 Feb 16;13(2):189. doi: 10.3390/antibiotics13020189.
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Antimicrobial Resistance: A Growing Serious Threat for Global Public Health.抗菌药物耐药性:对全球公共卫生日益严重的威胁。
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十年间克罗地亚全国性研究中牙科抗生素处方趋势
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Moral and Contextual Dimensions of "Inappropriate" Antibiotic Prescribing in Secondary Care: A Three-Country Interview Study.二级医疗中“不适当”抗生素处方的道德与情境维度:一项三国访谈研究
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