Bashkin Amir, Sharon Osnat, Zur Anita, Nakhleh Afif
Endocrinology and Diabetes Unit, Galilee Medical Center, Nahariya 2210001, Israel.
The Azrieli Faculty of Medicine, Bar-Ilan University, Safed 1311502, Israel.
J Clin Med. 2024 Dec 23;13(24):7866. doi: 10.3390/jcm13247866.
Ethnocultural differences between Jewish and Arab communities in Northern Israel may contribute to disparities in type 2 diabetes prevalence. Widespread screening strategies, including hospital-based initiatives, are crucial for early detection of hyperglycemia. This study aimed to determine the prevalence of postprandial hyperglycemia and identify its associated factors in a diverse population of non-diabetic adults visiting the Galilee Medical Center, a tertiary care hospital in Northern Israel. Participants were recruited between November 2017 and July 2023 through a voluntary screening program for non-diabetic adult visitors to the hospital. Capillary blood glucose measurements were obtained 1-4 h after a meal using a standardized glucometer. Postprandial hyperglycemia was defined as a blood glucose level ≥147 mg/dL, while postprandial normoglycemia was defined as ≤133 mg/dL. Individuals with glucose levels between 134-146 mg/dL were excluded from the analysis. Additional exclusion criteria included known diabetes, acute illness, corticosteroid use, and pregnancy. Demographic data, lifestyle factors, and health status were recorded. Propensity score matching was employed to ensure comparability between religious groups based on age, gender, and body mass index. Logistic regression analyses were conducted to identify independent predictors of postprandial hyperglycemia. 3457 adult visitors underwent postprandial glucose testing and met eligibility criteria. Following propensity score matching, 1845 participants (615 each from Druze, Jewish, and Muslim religious groups) were included in the final analysis. The prevalence of postprandial hyperglycemia was 9.4% in Druze, 6.0% in Jews, and 8.0% in Muslims ( = 0.08). Age >50 years was significantly associated with postprandial hyperglycemia in all groups. Obesity was associated with postprandial hyperglycemia in Muslims, with a similar non-significant trend in the Jewish cohort. Self-reported poor health was also associated with postprandial hyperglycemia in Muslims. In the Druze cohort, a low daily intake of daily fresh vegetable consumption was significantly associated with postprandial hyperglycemia. This study highlights the feasibility of hospital-based screening for postprandial hyperglycemia among adult visitors and reveals ethnic variations in prevalence and associated risk factors.
以色列北部犹太人和阿拉伯社区之间的种族文化差异可能导致2型糖尿病患病率的差异。广泛的筛查策略，包括基于医院的举措，对于早期发现高血糖至关重要。本研究旨在确定餐后高血糖的患病率，并在访问以色列北部一家三级护理医院加利利医疗中心的不同非糖尿病成年人群中识别其相关因素。2017年11月至2023年7月期间，通过针对非糖尿病成年访客的自愿筛查项目招募参与者。使用标准化血糖仪在餐后1 - 4小时测量毛细血管血糖。餐后高血糖定义为血糖水平≥147mg/dL，餐后血糖正常定义为≤133mg/dL。血糖水平在134 - 146mg/dL之间的个体被排除在分析之外。其他排除标准包括已知糖尿病、急性疾病、使用皮质类固醇和怀孕。记录人口统计学数据、生活方式因素和健康状况。采用倾向评分匹配以确保基于年龄、性别和体重指数的宗教群体之间具有可比性。进行逻辑回归分析以识别餐后高血糖的独立预测因素。3457名成年访客接受了餐后血糖检测并符合入选标准。经过倾向评分匹配后，1845名参与者（德鲁兹、犹太和穆斯林宗教群体各615名）被纳入最终分析。德鲁兹人群中餐后高血糖的患病率为9.4%，犹太人为6.0%，穆斯林为8.0%（P = 0.08）。所有群体中，年龄>50岁与餐后高血糖显著相关。肥胖与穆斯林的餐后高血糖相关，在犹太人群体中有类似的非显著趋势。自我报告健康状况不佳也与穆斯林的餐后高血糖相关。在德鲁兹人群中，每日新鲜蔬菜摄入量低与餐后高血糖显著相关。本研究强调了对成年访客进行基于医院的餐后高血糖筛查的可行性，并揭示了患病率和相关危险因素的种族差异。
