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体外循环冠状动脉旁路移植术吻合术中冲洗雾与二氧化碳对比直接二氧化碳吹入法的比较分析:脱夹时的疗效、效率及颤动情况和微栓塞气体活性发生率

Comparative Analysis of Irrigation Mist and CO vs. Direct CO Blower in On-Pump Coronary Artery Bypass Grafting Anastomosis: Efficacy, Efficiency, and Fibrillation upon De-Clamping and Micro-Embolic Gas Activity Incidence.

作者信息

Condello Ignazio, Speziale Giuseppe, Fiore Flavio, Nasso Giuseppe

机构信息

Department of Cardiac Surgery, Anthea Hospital GVM Care and Research, Via Camillo Rosalba 35/37, 70124 Bari, Italy.

出版信息

Medicina (Kaunas). 2024 Dec 10;60(12):2035. doi: 10.3390/medicina60122035.

DOI:10.3390/medicina60122035
PMID:39768915
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11728404/
Abstract

In coronary artery bypass grafting (CABG) on pump, achieving optimal visualization is critical for surgical precision and safety. The use of blowers to clear the CABG anastomosis poses risks, including the formation of micro-embolic gas bubbles, which can be insidious and increase the risk of cerebral or myocardial complications. This retrospective study compares the effectiveness of the use of irrigation mist and CO versus a direct CO blower without irrigation in terms of visualization, postoperative fibrillation, and micro-embolic gas activity. The study involved 40 patients who underwent on-pump CABG, with 20 patients assigned to the irrigation mist and CO group (ClearView™) and 20 to the direct CO blower group. Primary outcomes included the quality of intraoperative visualization, the incidence of fibrillation at aortic de-clamping, and the presence of micro-embolic gas activity detected via transesophageal echocardiography (TEE) in the cardiac chambers. Patients in the irrigation mist and CO group experienced superior visualization and reduced tissue desiccation. Fibrillation at the time of aortic de-clamping occurred in two patients (10%) using the irrigation mist and CO, compared to eight patients (40%) using the direct CO blower. Additionally, TEE monitoring revealed lower levels of micro-embolic gas activity in the irrigation mist and CO group, indicating a potential reduction in gas embolization risk. The irrigation mist and CO system not only provides enhanced visualization during CABG but also significantly reduces the incidence of fibrillation during aortic de-clamping and micro-embolic gas activity. These findings suggest improved patient safety and outcomes, highlighting the irrigation mist and CO system as a potentially safer alternative to direct CO blowing in the context of myocardial revascularization.

摘要

在体外循环冠状动脉搭桥术(CABG)中,实现最佳可视化对于手术的精确性和安全性至关重要。使用吹风机清除CABG吻合口存在风险,包括形成微栓塞气泡,这些气泡可能很隐匿,并增加脑或心肌并发症的风险。这项回顾性研究比较了在可视化、术后房颤和微栓塞气体活动方面,使用冲洗雾和二氧化碳与直接使用无冲洗的二氧化碳吹风机的效果。该研究纳入了40例行体外循环CABG的患者,其中20例被分配到冲洗雾和二氧化碳组(ClearView™),20例被分配到直接二氧化碳吹风机组。主要结局包括术中可视化质量、主动脉夹闭时房颤的发生率以及通过经食管超声心动图(TEE)检测到的心腔内微栓塞气体活动情况。冲洗雾和二氧化碳组的患者可视化效果更好,组织干燥程度降低。使用冲洗雾和二氧化碳时,主动脉夹闭时房颤发生在2例患者(10%),而使用直接二氧化碳吹风机时为8例患者(40%)。此外,TEE监测显示冲洗雾和二氧化碳组的微栓塞气体活动水平较低,表明气体栓塞风险可能降低。冲洗雾和二氧化碳系统不仅在CABG期间提供了更好的可视化,而且显著降低了主动脉夹闭时房颤的发生率和微栓塞气体活动。这些发现表明患者安全性和结局得到改善,突出了冲洗雾和二氧化碳系统在心肌血运重建中作为直接二氧化碳吹气潜在更安全替代方案的地位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/3dba620cd77b/medicina-60-02035-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/fda75def09b2/medicina-60-02035-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/888720c56620/medicina-60-02035-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/1a958a70a7e1/medicina-60-02035-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/cb7c5e385284/medicina-60-02035-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/3dba620cd77b/medicina-60-02035-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/fda75def09b2/medicina-60-02035-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/888720c56620/medicina-60-02035-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/1a958a70a7e1/medicina-60-02035-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/cb7c5e385284/medicina-60-02035-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffbd/11728404/3dba620cd77b/medicina-60-02035-g005.jpg

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本文引用的文献

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Conventional versus minimally invasive extra-corporeal circulation in patients undergoing cardiac surgery: A randomized controlled trial (COMICS).心脏手术患者常规体外循环与微创体外循环的比较:一项随机对照试验(COMICS)
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Carbon Dioxide Blower Facilitates Visceral Pleurectomy in Malignant Pleural Mesothelioma.二氧化碳吹吸器有助于恶性胸膜间皮瘤的内脏层胸膜切除术。
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MIDCAB Tips and tricks for a successful procedure.
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Carbon dioxide embolism induced right coronary artery ischaemia during off-pump obtuse marginalis artery grafting.非体外循环下钝缘支动脉桥接术时发生二氧化碳栓塞导致右冠状动脉缺血。
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Simple on-site assembled blower-mister device provides sufficient humidification and visualization in off-pump surgery.简易现场组装的吹雾器装置在非体外循环心脏手术中可提供充足的湿度并具备可视化效果。
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