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大鼠肝外器官中的贮脂细胞

Pit cells in extrahepatic organs of the rat.

作者信息

Kaneda K, Wake K

出版信息

Anat Rec. 1985 Feb;211(2):192-7. doi: 10.1002/ar.1092110211.

DOI:10.1002/ar.1092110211
PMID:3977086
Abstract

Electron microscopic examination of the extrahepatic distribution of pit cells, a cell type found in the liver, revealed their existence in several other organs of the rat. They were relatively frequent in lungs, spleen (red pulp), small intestine, epididymis, trachea, and peripheral blood; much fewer in bone marrow and thymus (medulla); and nonexistent in lymph nodes, spleen (white pulp), and thymus (cortex). The pit cells in these organs, as well as in the liver, contained characteristic dense granules and rod-cored vesicles in the cytoplasm. Our observations suggest that pit cells circulating in the peripheral blood adhere to the endothelium of capillaries in the various organs and migrate into the tissue, where they have some special immunological function.

摘要

对肝外pit细胞(一种存在于肝脏中的细胞类型)分布进行的电子显微镜检查显示,它们也存在于大鼠的其他几个器官中。它们在肺、脾(红髓)、小肠、附睾、气管和外周血中相对常见;在骨髓和胸腺(髓质)中较少;在淋巴结、脾(白髓)和胸腺(皮质)中不存在。这些器官以及肝脏中的pit细胞在细胞质中含有特征性的致密颗粒和杆状核心小泡。我们的观察结果表明,在外周血中循环的pit细胞粘附于各器官毛细血管的内皮,并迁移到组织中,在那里它们具有一些特殊的免疫功能。

相似文献

1
Pit cells in extrahepatic organs of the rat.大鼠肝外器官中的贮脂细胞
Anat Rec. 1985 Feb;211(2):192-7. doi: 10.1002/ar.1092110211.
2
Circulation and migration of small blood lymphocytes in the rat. I. Kinetics of lymphocyte circulation in the lymphoid organs.大鼠小淋巴细胞的循环与迁移。I. 淋巴细胞在淋巴器官中的循环动力学。
Am J Pathol. 1978 Dec;93(3):623-38.
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Kinetics of the distribution of thymus and marrow cells in the peripheral lymphoid organs of the mouse: ecotaxis.小鼠外周淋巴器官中胸腺和骨髓细胞的分布动力学:生态趋向性。
Clin Exp Immunol. 1971 Sep;9(3):371-80.
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[Method of determination of the total number of cells in different organs of experimental animals].[实验动物不同器官中细胞总数的测定方法]
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[Observations on the differentiation of the mesenchymal cells in thymectomized rats].[对胸腺切除大鼠间充质细胞分化的观察]
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Migratory patterns of different indium-111 labeled leukocyte populations (chiefly lymphocytes) from control and thymectomized rats.来自对照大鼠和胸腺切除大鼠的不同铟 - 111标记白细胞群体(主要是淋巴细胞)的迁移模式。
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引用本文的文献

1
Quantitative analysis of rod-cored vesicles and dense granules of large granular lymphocytes in the liver, spleen, and peripheral blood of rats.
Cell Tissue Res. 1994 Apr;276(1):187-95. doi: 10.1007/BF00354799.
2
Expression and rearrangement of the alpha, beta, and gamma chain genes of the T cell receptor in cloned murine large granular lymphocyte lines. No correlation with the cytotoxic spectrum.T细胞受体α、β和γ链基因在克隆的小鼠大颗粒淋巴细胞系中的表达与重排。与细胞毒性谱无相关性。
J Exp Med. 1986 Aug 1;164(2):428-42. doi: 10.1084/jem.164.2.428.