Kaneda K, Wake K
Anat Rec. 1985 Feb;211(2):192-7. doi: 10.1002/ar.1092110211.
Electron microscopic examination of the extrahepatic distribution of pit cells, a cell type found in the liver, revealed their existence in several other organs of the rat. They were relatively frequent in lungs, spleen (red pulp), small intestine, epididymis, trachea, and peripheral blood; much fewer in bone marrow and thymus (medulla); and nonexistent in lymph nodes, spleen (white pulp), and thymus (cortex). The pit cells in these organs, as well as in the liver, contained characteristic dense granules and rod-cored vesicles in the cytoplasm. Our observations suggest that pit cells circulating in the peripheral blood adhere to the endothelium of capillaries in the various organs and migrate into the tissue, where they have some special immunological function.
对肝外pit细胞(一种存在于肝脏中的细胞类型)分布进行的电子显微镜检查显示,它们也存在于大鼠的其他几个器官中。它们在肺、脾(红髓)、小肠、附睾、气管和外周血中相对常见;在骨髓和胸腺(髓质)中较少;在淋巴结、脾(白髓)和胸腺(皮质)中不存在。这些器官以及肝脏中的pit细胞在细胞质中含有特征性的致密颗粒和杆状核心小泡。我们的观察结果表明,在外周血中循环的pit细胞粘附于各器官毛细血管的内皮,并迁移到组织中,在那里它们具有一些特殊的免疫功能。