da Silva Caroline G F, Petró Rafaela R, de Castro Jéssica H, Almeida Rafael N, Cassel Eduardo, Vargas Rubem M F
Unit Operations Lab, School of Technology, Pontifical Catholic University of Rio Grande do Sul, Av. Ipiranga 6681-Prédio 30, Bloco F, Sala 208, Porto Alegre 90619-900, Brazil.
Pharmaceutics. 2024 Dec 5;16(12):1560. doi: 10.3390/pharmaceutics16121560.
Degradation by physical and chemical agents affects the properties of essential oils; therefore, this study aimed to protect the volatile compounds present in essential oils through biopolymer encapsulation. The (Lam) DC. essential oil was obtained by steam distillation at 2.5 bar. The nano-sized physical coating of the active oil core resulted in an optimal polymer/oil ratio of 1:3 and particle diameter of 178 nm. The particle morphology was evaluated using scanning electron microscopy and transmission electron microscopy. The inclusion of the essential oil in the polymer was confirmed using thermogravimetric analysis. The pH of the formulation remained stable for 90 days, and controlled release and encapsulation efficiencies were evaluated. Formulations were evaluated using the perfumery radar technique, which indicated a predominantly woody profile. The diffusion of fragrant compounds in the air was assessed over time and mathematically modeled. The produced nanostructures were efficient for the controlled release of volatile compounds from the essential oil of .
物理和化学试剂导致的降解会影响精油的特性；因此，本研究旨在通过生物聚合物包封来保护精油中存在的挥发性化合物。通过在2.5巴压力下进行水蒸气蒸馏获得了（Lam）DC.精油。活性油核的纳米级物理涂层产生了1:3的最佳聚合物/油比例和178纳米的粒径。使用扫描电子显微镜和透射电子显微镜评估颗粒形态。使用热重分析确认了聚合物中精油的包合情况。制剂的pH值在90天内保持稳定，并评估了控释和包封效率。使用香料雷达技术对制剂进行评估，结果表明其主要具有木质香气特征。对香气化合物在空气中的扩散随时间进行了评估并进行了数学建模。所制备的纳米结构对于从.精油中控制释放挥发性化合物是有效的。
