硝酸银对克氏锥虫烟酰胺腺嘌呤二核苷酸磷酸连接的谷氨酸脱氢酶的抑制作用。
Inhibition of the NADP-linked glutamate dehydrogenase from Trypanosoma cruzi by silver nitrate.
作者信息
Juan S M, Segura E L, Cazzulo J J
出版信息
Experientia. 1979 Sep 15;35(9):1139-40. doi: 10.1007/BF01963246.
PMID:39772
Abstract
The purified NADP-linked glutamate dehydrogenase from Trypanosoma cruzi was strongly inhibited by silver nitrate. The inhibition was reversed by reduced glutathione, and was modified by the presence of the substrates during preincubation of the enzyme with the inhibitor.
摘要
来自克氏锥虫的纯化的烟酰胺腺嘌呤二核苷酸磷酸（NADP）连接的谷氨酸脱氢酶受到硝酸银的强烈抑制。这种抑制作用可被还原型谷胱甘肽逆转，并且在酶与抑制剂预孵育期间，底物的存在会改变这种抑制作用。
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