Carrera G, Boigegrain R A, Mitjavila S
Ann Nutr Metab. 1985;29(1):56-62. doi: 10.1159/000176954.
Rats were subjected to fasting-induced mobilization of a quantity of DDT equivalent to 45% of the LD50. They were then fed for 1 week for a nutritional and toxicological study. Mobilization of DDT by starvation had no apparent effect on the activity of the various enzymes or the weight of the organs measured at the end of the refeeding period. The animals which had received DDT pretreatment showed higher protein efficiency than the control animals. Only the level of body lipids was lower in the animals pretreated with DDT, although the quantities of lipids stored during the study period were identical in both groups of animals. Overall, the results show that the nutritional state of the two groups of animals was very similar at the end of the refeeding period.
让大鼠经历禁食诱导的相当于半数致死剂量(LD50)45%的滴滴涕(DDT)动员。然后给它们喂食1周,进行营养和毒理学研究。饥饿导致的滴滴涕动员对再喂养期结束时所测的各种酶的活性或器官重量没有明显影响。接受过滴滴涕预处理的动物比对照动物表现出更高的蛋白质效率。尽管两组动物在研究期间储存的脂质数量相同,但仅用滴滴涕预处理的动物体内脂质水平较低。总体而言,结果表明,在再喂养期结束时,两组动物的营养状况非常相似。