Gerstmeyer Julius, Pierre Clifford, Schildhauer Thomas A, Abdul-Jabbar Amir, Oskouian Rod J, Chapman Jens R
Swedish Neuroscience Institute, Swedish Medical Center, Seattle 550 17th Avenue, Suite 500, Seattle, WA, 98122, USA.
Seattle Science Foundation, 550 17th Avenue, Suite 600, Seattle, WA, 98122, USA.
J Orthop Surg Res. 2025 Jan 7;20(1):17. doi: 10.1186/s13018-024-05431-2.
Spondylodiscitis presents a significant diagnostic and treatment challenge to healthcare providers, with various risk factors and treatment outcomes having been identified. Malnutrition, a multifactorial condition defined by imbalance or deficiency of nutrients, is a known risk factor for various adverse events such as postoperative infection and readmissions in spine surgery. However, its impact in SD has not yet been explored. The study aims to assess the prevalence of malnutrition and hypoalbuminemia in SD patients and their impact on the 90-day-all-cause readmission and in-hospital mortality rates.
Using the 2020 Nationwide Readmission Database, adult patients were selected by primary ICD-10 diagnosis for SD (M46.2x, M46.3x and M46.4x). Demographic information and clinical data were extracted. Readmissions were identified by VisitLink. Patients were categorized into 2 groups: those with malnutrition and/or hypoalbuminemia and those without. Descriptive and comparative analysis, with multivariate regression models to assess for independent risk factors of mortality and readmission were performed.
Using the 2020 Nationwide Readmission Database, adult patients were selected by primary ICD-10 diagnosis for SD (M46.2x, M46.3x and M46.4x). Demographic information and clinical data were extracted. Readmissions were identified by VisitLink. Patients were categorized into 2 groups: those with malnutrition and/or hypoalbuminemia and those without. Descriptive and comparative analysis, with multivariate regression models to assess for independent risk factors of mortality and readmission were performed.
Malnutrition and hypoalbuminemia are relatively common in SD patients and are significant risk factors for both in-hospital mortality and readmission. Early identification, including screening for hypoalbuminemia and management of malnutrition, may be beneficial in SD treatment.
脊柱椎间盘炎给医疗服务提供者带来了重大的诊断和治疗挑战,已确定了各种风险因素和治疗结果。营养不良是一种由营养失衡或缺乏定义的多因素病症,是诸如脊柱手术后感染和再入院等各种不良事件的已知风险因素。然而,其在脊柱椎间盘炎中的影响尚未得到探讨。本研究旨在评估脊柱椎间盘炎患者中营养不良和低白蛋白血症的患病率及其对90天全因再入院率和住院死亡率的影响。
使用2020年全国再入院数据库,通过原发性ICD-10诊断为脊柱椎间盘炎(M46.2x、M46.3x和M46.4x)来选择成年患者。提取人口统计学信息和临床数据。通过VisitLink识别再入院情况。患者被分为两组:有营养不良和/或低白蛋白血症的患者和没有的患者。进行描述性和比较性分析,并使用多变量回归模型评估死亡率和再入院的独立风险因素。
营养不良和低白蛋白血症在脊柱椎间盘炎患者中相对常见,并且是住院死亡率和再入院的重要风险因素。早期识别,包括筛查低白蛋白血症和管理营养不良,可能对脊柱椎间盘炎的治疗有益。