Oliveira Andressa Feitosa Bezerra de, Nunes Vitória Régia Rolim, Cunha Juliellen Luiz da, Forte Anderson Gomes, Andrade Arthur Felipe de Brito, Fernandes Nayanna Lana Soares, Pereira Ana Maria Barros Chaves, D'Alpino Paulo Henrique Perlatti, Sampaio Fábio Correia
Universidade Federal da Paraíba - UFPB, Health Science Center, Department of Morphology ,João Pessoa, PB, Brazil.
Universidade Federal da Paraíba - UFPB, School of Dentistry, Institutional Scientific Initiation Scholarship Program, João Pessoa, PB, Brazil.
Braz Oral Res. 2024 Dec 20;38:e139. doi: 10.1590/1807-3107bor-2024.vol38.0139. eCollection 2024.
This study aimed to evaluate the effectiveness of bioactive toothpastes in remineralizing eroded enamel surfaces in vitro. Bovine enamel blocks (n = 48) were obtained and classified into untreated, demineralized, and treated areas. Specimens were randomly classified into six groups (n = 8 each): fluoride-free toothpaste (NCT), Colgate Total 12 (PCT), Sensodyne Repair and Protect (SRP), Sensodyne Pronamel (SPE), Regenerador + Sensitive (RGS), and RGS/calcium booster (RCB). The specimens were subjected to erosive pH cycling for 5 days for 4 times/day (90 s) and treated with toothpaste slurries (1:3) for 1 min. The Vickers hardness (50 g/10 s) and percentage surface hardness recovery (%SMHR) were calculated. Furthermore, the topography and roughness (Ra) of the enamel surface were evaluated using a 3D non-contact optical profilometer, along with the tooth surface loss (TSL). Data were statistically analyzed using analysis of variance or Tukey's test (significance: 5%). The %SMHR of the SRP and NCT groups were significantly lower than those of the other groups (p < 0.05). Ra was higher when the eroded area was treated with SRP and SPE (p < 0.05). Treatment with RGS, PCT, and SPE favored the recovery of the enamel surface compared with the NCT group (p < 0.05). The best TSL results were obtained with treatment with RGS, followed by PCT and SPE (p < 0.05). The RCB group showed statistically equivalent results for surface hardness recovery and TSL (p > 0.05). Conclusively, PCT and RGS toothpastes were more effective in remineralizing the enamel surface.
本研究旨在评估生物活性牙膏在体外对侵蚀性牙釉质表面进行再矿化的有效性。获取牛牙釉质块（n = 48），并将其分为未处理、脱矿和处理区域。样本被随机分为六组（每组n = 8）：无氟牙膏（NCT）、高露洁全效12（PCT）、舒适达修复与保护（SRP）、舒适达专业修复（SPE）、Regenerador + Sensitive（RGS）以及RGS/钙增强剂（RCB）。样本每天进行4次、每次90秒的侵蚀性pH循环处理，持续5天，并用牙膏浆液（1:3）处理1分钟。计算维氏硬度（50 g/10 s）和表面硬度恢复百分比（%SMHR）。此外，使用三维非接触光学轮廓仪评估牙釉质表面的形貌和粗糙度（Ra），以及牙齿表面损失（TSL）。数据采用方差分析或Tukey检验进行统计学分析（显著性：5%）。SRP组和NCT组的%SMHR显著低于其他组（p < 0.05）。用SRP和SPE处理侵蚀区域时，Ra较高（p < 0.05）。与NCT组相比，用RGS、PCT和SPE处理有利于牙釉质表面的恢复（p < 0.05）。用RGS处理获得的TSL结果最佳，其次是PCT和SPE（p < 0.05）。RCB组在表面硬度恢复和TSL方面显示出统计学上等效的结果（p > 0.05）。总之，PCT和RGS牙膏在牙釉质表面再矿化方面更有效。
