Schilcher A V, Geerling G
Klinik für Augenheilkunde, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.
Ophthalmologie. 2025 Jan;122(1):12-19. doi: 10.1007/s00347-024-02167-6. Epub 2025 Jan 7.
The ocular surface is directly exposed to environmental influences. Noxae that have already been identified for the ocular surface are heat, air dryness, pollutant gases, fine dust particles and ultraviolet radiation.
The current literature was used to investigate the relationship between frequent ocular surface diseases and various environmental factors and to analyze their development over the years.
Epidemiological studies on dry eye disease and allergic conjunctivitis have shown an increase in the incidences in recent years. Environmental pollutants have been identified as disease triggers. In addition, the prolonged pollen season and increased pollen concentrations are also risk factors. There is also a higher prevalence of pterygium in population groups with high UV exposure. Other diseases with potential environmental pathogenesis are acute photokeratitis, photoconjunctivitis and malignant melanoma of the conjunctiva.
For ocular surface diseases, large epidemiological cohorts have shown climate-related increases in the incidence. A further increase in environmentally associated noxious substances can be expected in the coming decades. In addition to measures to mitigate climate change, the underlying mechanisms of disease development and new approaches to prevention and treatment, such as room humidification, air filters or contact lenses with UV filters, should be investigated.
眼表直接暴露于环境影响之下。已确定对眼表有害的因素包括热、空气干燥、污染气体、细尘颗粒和紫外线辐射。
利用当前文献研究常见眼表疾病与各种环境因素之间的关系,并分析这些因素多年来的发展情况。
关于干眼病和过敏性结膜炎的流行病学研究表明,近年来其发病率有所上升。环境污染物已被确定为疾病触发因素。此外,花粉季节延长和花粉浓度增加也是危险因素。在紫外线暴露量高的人群中,翼状胬肉的患病率也较高。其他具有潜在环境致病机制的疾病包括急性光角膜炎、光结膜炎和结膜恶性黑色素瘤。
对于眼表疾病,大型流行病学队列研究表明其发病率与气候相关且呈上升趋势。预计在未来几十年,与环境相关的有害物质还会进一步增加。除了采取缓解气候变化的措施外,还应研究疾病发展的潜在机制以及预防和治疗的新方法,如室内加湿、空气过滤器或带紫外线过滤器的隐形眼镜。