A blood test for Alzheimer's disease: a decade of progress and success.
作者信息
Ashton Nicholas J, Zetterberg Henrik
机构信息
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; Banner Alzheimer's Institute, Phoenix, AZ, USA; Banner Sun Health Research Institute, Sun City, AZ, USA.
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Neurodegenerative Disease, Institute of Neurology, UCL, London, UK; UK Dementia Research Institute, UCL, London, UK; Hong Kong Center for Neurodegenerative Diseases, Clear Water Bay, Hong Kong, China; Wisconsin Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
出版信息
EBioMedicine. 2025 Feb;112:105545. doi: 10.1016/j.ebiom.2024.105545. Epub 2025 Jan 7.
Abstract
摘要
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本文引用的文献
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Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup.修订的阿尔茨海默病诊断和分期标准：阿尔茨海默病协会工作组。
Alzheimers Dement. 2024 Aug;20(8):5143-5169. doi: 10.1002/alz.13859. Epub 2024 Jun 27.
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Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease.阿尔茨海默病中 8 种血浆淀粉样蛋白β 42/40 分析物的对头比较。
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High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis.高精度血浆β-淀粉样蛋白 42/40 可预测当前和未来的脑淀粉样变。
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Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography.血浆磷酸化 tau181 随着阿尔茨海默病临床严重程度的增加而增加，与 tau 和淀粉样蛋白正电子发射断层扫描相关。
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