Hameed Iman, Al-Habbal Yahya
Department of Upper Gastrointestinal/Hepatobiliary Surgery, Western Hospital, Footscray, VIC 3011, Australia.
Department of Upper Gastrointestinal/Hepatobiliary Surgery, Western Hospital, Footscray, VIC 3011, Australia.
Int J Surg Case Rep. 2025 Feb;127:110853. doi: 10.1016/j.ijscr.2025.110853. Epub 2025 Jan 6.
Haemobilia causing obstructive jaundice is a rare complication with most occurrences reported post instrumentation e.g. endoscopic retrograde cholangiopancreatography (ERCP), percutaneous transhepatic cholangioagraphy (PTC) and, trans-cystic duct exploration or due to hepatic tree pseudoaneurysms. Traumatic haemobilia typically presents with the classical triad of right upper quadrant pain, jaundice and upper gastrointestinal bleeding. On imaging, an obstructed biliary tree is commonly found dilated.
We report a case of a large obstructing blood clot causing biliary sepsis for a patient on oral anticoagulation. The patient had no classical triad findings or demonstrable evidence of biliary obstruction on imaging. The patient was managed with clot retrieval via ERCP and sphincterotomy; anticoagulant was resumed seven days post procedure.
Haemobilia is a rare consequence in patients on anticoagulation therapy. The management principles are coagulopathy correction and obstruction relief. The pathophysiology in patients without bleeding disorders remains unknown.
Although rare, haemobilia can be a cause of obstructive jaundice for a patient on anticoagulation.
引起梗阻性黄疸的胆道出血是一种罕见的并发症,大多数病例报告发生在器械操作后,如内镜逆行胰胆管造影术(ERCP)、经皮经肝胆管造影术(PTC)、经胆囊管探查术,或由肝内假性动脉瘤引起。外伤性胆道出血通常表现为右上腹疼痛、黄疸和上消化道出血的典型三联征。在影像学检查中,通常发现梗阻性胆管树扩张。
我们报告一例口服抗凝药的患者因巨大阻塞性血凝块导致胆系感染。该患者没有典型的三联征表现,影像学检查也没有明显的胆道梗阻证据。患者通过ERCP和括约肌切开术进行血凝块取出治疗;术后7天恢复抗凝治疗。
抗凝治疗患者发生胆道出血是一种罕见的后果。治疗原则是纠正凝血功能障碍和解除梗阻。无出血性疾病患者的病理生理机制尚不清楚。
尽管罕见,但胆道出血可能是抗凝治疗患者梗阻性黄疸的一个原因。