[原发性动脉高血压高危人群红细胞内钠离子活性的评估及其在与继发性高血压鉴别诊断中的辅助作用]

[Evaluation of intra-erythrocyte Na+ activity in persons at high risk for essential arterial hypertension and as an aid in differential diagnosis from secondary forms of hypertension].

作者信息

Antonicelli R, Coppa G, Piani M, Sturbini S, Testa I, Russo P

出版信息

Boll Soc Ital Biol Sper. 1985 Jan 30;61(1):159-64.

Abstract

The intracellular "Na+ activity" was measured in erythrocytes of normotensive subjects (46), in essential hypertensive patients (18), in their children (20) and in patients with secondary hypertension (8). In normotensive subjects without a genetic trait of hypertension intracellular "Na+ activity" was 7.3 +/- 0.8 mmol/l, in secondary hypertensive patients was 7.5 +/- 0.6 mmol/l, in essential hypertensive patients was 10.9 +/- 1.1 mmol/l and in their children was 8.6 +/- 2.1 mmol/l. In this group (children) it was possible to differentiate between 2 population, the 1 degree with height intracellular "Na+ activity" (8); the 2 degrees with normal intracellular "Na+ activity".

摘要

在血压正常者（46例）、原发性高血压患者（18例）、他们的子女（20例）以及继发性高血压患者（8例）的红细胞中测量细胞内“钠离子活性”。在无高血压遗传特征的血压正常者中，细胞内“钠离子活性”为7.3±0.8 mmol/L，在继发性高血压患者中为7.5±0.6 mmol/L，在原发性高血压患者中为10.9±1.1 mmol/L，在他们的子女中为8.6±2.1 mmol/L。在该组（子女）中，可以区分出2类人群，第1类细胞内“钠离子活性”较高（8例）；第2类细胞内“钠离子活性”正常。