Garay R P, Elghozi J L, Dagher G, Meyer P
N Engl J Med. 1980 Apr 3;302(14):769-71. doi: 10.1056/NEJM198004033021402.
An abnormally low sodium-potassium net flux ratio in erythrocytes was recently described in human essential hypertension. We have confirmed this finding in 65 patients with essential hypertension who were compared with 33 normotensive controls born of normotensive parents. In 23 other subjects with documented secondary hypertension and normotensive parents, the sodium-potassium net flux ratio was found to be similar to that in the controls. The erythrocyte test thus appears to be of interest in distinguishing between essential and secondary hypertension. Severe renal failure itself reduces the flux ratio and would therefore distort the results of this test.
最近在人类原发性高血压中发现红细胞钠钾净通量比率异常低。我们在65例原发性高血压患者中证实了这一发现，并将他们与33名父母血压正常的血压正常对照者进行了比较。在另外23名有继发性高血压记录且父母血压正常的受试者中，发现钠钾净通量比率与对照组相似。因此，红细胞检测在区分原发性和继发性高血压方面似乎很有意义。严重肾衰竭本身会降低通量比率，因此会扭曲该检测的结果。
