Moradkhani Asra, Mohammadzadeh Pardis, Assadi Srwa, Saed Lotfolah, Baradaran Hamid Reza, Moradi Yousef
Student of the Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
BMC Endocr Disord. 2025 Jan 8;25(1):8. doi: 10.1186/s12902-024-01797-w.
Considering, the changes in lifestyle during the last decade the main aim of this study was to investigate the pooled prevalence of metabolic syndrome (MetS) and its components in Iran.
For implementing a comprehensive search strategy related to the objectives of the present meta-analysis, all international databases like PubMed (Medline), Scopus, Embase, Web of Sciences (Elsevier), and CINHAL were searched up to January 2024. The quality of the final selected studies was evaluated according to the Joanna Briggs Institute Critical Appraisal (JBI) tool for analytical cross-sectional studies. The subgroup analysis was performed based on gender, province, area, criteria of diagnosis, and components of metabolic syndrome. All of the analyses were carried out in STATA version 17.
Among 2,034 relevant primary studies, 194 articles were entered into the meta-analysis. the prevalence of MetS in Iran was assessed using various criteria. The overall pooled prevalence was (31%, 95% CI: 28-34%), with a higher occurrence in females and individuals aged over 65 years. The central region, particularly Qom, reported the highest prevalence, while Tehran had the lowest. Low HDL cholesterol and waist circumference were the most common MetS components. The study provides critical data for health policy and intervention strategies in Iran.
Higher rates in females and the elderly and the predominance of low HDL cholesterol and waist circumference as MetS components call for targeted public health interventions. These insights are pivotal for formulating strategic health policies to mitigate MetS and its impact on the Iranian population.
考虑到过去十年生活方式的变化，本研究的主要目的是调查伊朗代谢综合征（MetS）及其组成成分的合并患病率。
为实施与本荟萃分析目标相关的全面搜索策略，检索了截至2024年1月的所有国际数据库，如PubMed（Medline）、Scopus、Embase、Web of Sciences（Elsevier）和CINHAL。根据乔安娜·布里格斯研究所分析性横断面研究的批判性评价（JBI）工具评估最终选定研究的质量。基于性别、省份、地区、诊断标准和代谢综合征的组成成分进行亚组分析。所有分析均在STATA 17版本中进行。
在2034项相关的原始研究中，有194篇文章纳入了荟萃分析。使用各种标准评估了伊朗MetS的患病率。总体合并患病率为（31%，95%CI：28 - 34%），女性和65岁以上个体的患病率更高。中部地区，特别是库姆，报告的患病率最高，而德黑兰的患病率最低。低高密度脂蛋白胆固醇和腰围是最常见的MetS组成成分。该研究为伊朗的卫生政策和干预策略提供了关键数据。
女性和老年人中的较高患病率以及低高密度脂蛋白胆固醇和腰围作为MetS组成成分的主导地位，需要有针对性的公共卫生干预措施。这些见解对于制定战略卫生政策以减轻MetS及其对伊朗人口的影响至关重要。
