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低能量精细脉冲光疗法治疗敏感性皮肤:一项回顾性研究

Low-Energy Delicate Pulsed Light Therapy for Sensitive Skin: A Retrospective Study.

作者信息

Fu Yujie, Quan Yue, Zhao Wanxing, Liu Zhaoyang, Peng Jiao, Pang Xinyue, Zhao Boyu, Tan Lisha, Zhou Quan, Shao Lili, Wang Huiping, Hou Shuping

机构信息

Department of Dermatovenereology, Tianjin Medical University General Hospital/Tianjin Institute of Sexually Transmitted Disease, Tianjin, China.

出版信息

J Cosmet Dermatol. 2025 Jan;24(1):e16781. doi: 10.1111/jocd.16781.

Abstract

BACKGROUND

Sensitive skin (SS) is a multifactorial syndrome that affects about half of the world's population. However, there is no standardized treatment protocol. Photovoltaic technology has been widely used in recent years for the treatment of sensitive skin, but the efficacy of low-energy delicate pulsed light (DPL) in the treatment of sensitive skin is unknown.

OBJECTIVE

To explore the efficacy and safety of low-energy DPL treatment for sensitive skin.

METHODS

This study included 181 patients with SS who attended the Department of Dermatology from January 2019 to January 2022. All patients were treated with DPL (5.0-6.8 J/cm). Patients received varying durations of DPL, with 4-week intervals based on the severity of their condition. Sensitivity scores at baseline and final treatment were collected using a 10-item sensitivity scale (SS-10). Facial erythema was assessed through the Clinician Erythema Assessment Scale (CEA) based on facial photographs taken at each visit. VISIA-CR was used to visualize and analyze facial redness at baseline and after the final treatment, and erythema values were recorded. Adverse reactions were documented during each treatment session.

RESULTS

Among 181 patients, 86 were SS alone, 32 were rosacea with SS, 32 were acne with SS, and 31 were dermatitis with SS. A significant difference was observed between patients' baseline and final SS-10 scores (p < 0.001). Statistically significant differences were found between the patients' CEA scores at different visits (p < 0.001). Clinical photographs demonstrated significant improvements in facial redness and skin color. VISIA-CR analysis showed a considerable reduction in erythema values at the final treatment visit compared to baseline (p < 0.001). No obvious adverse effects were observed in any of the patients.

CONCLUSION

Low-energy DPL is an effective and safe treatment for sensitive skin.

摘要

背景

敏感性皮肤(SS)是一种多因素综合征,影响着全球约一半的人口。然而,目前尚无标准化的治疗方案。近年来,光疗技术已广泛应用于敏感性皮肤的治疗,但低能量精准脉冲光(DPL)治疗敏感性皮肤的疗效尚不清楚。

目的

探讨低能量DPL治疗敏感性皮肤的疗效和安全性。

方法

本研究纳入了2019年1月至2022年1月在皮肤科就诊的181例SS患者。所有患者均接受DPL治疗(5.0 - 6.8 J/cm)。根据病情严重程度,患者接受不同疗程的DPL治疗,间隔4周。使用10项敏感性量表(SS - 10)收集基线和最终治疗时的敏感性评分。通过临床医师红斑评估量表(CEA),根据每次就诊时拍摄的面部照片评估面部红斑。使用VISIA - CR在基线和最终治疗后对面部发红情况进行可视化分析,并记录红斑值。每次治疗期间记录不良反应。

结果

181例患者中,单纯SS患者86例,玫瑰痤疮合并SS患者32例,痤疮合并SS患者32例,皮炎合并SS患者31例。患者的基线和最终SS - 10评分之间存在显著差异(p < 0.001)。不同就诊时患者的CEA评分之间存在统计学显著差异(p < 0.001)。临床照片显示面部发红和肤色有显著改善。VISIA - CR分析显示,与基线相比,最终治疗就诊时红斑值显著降低(p < 0.001)。所有患者均未观察到明显不良反应。

结论

低能量DPL是治疗敏感性皮肤的一种有效且安全的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42c1/11711946/e66e5da6844d/JOCD-24-e16781-g003.jpg

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