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巨大神经节神经瘤所致青少年胸段脊柱侧弯:两例报告及文献复习

Adolescent thoracic scoliosis due to giant ganglioneuroma: a two-case report and literature review.

作者信息

Dinh Hoai Thi Phuong, Yamato Yu, Hasegawa Tomohiko, Yoshida Go, Banno Tomohiro, Arima Hideyuki, Oe Shin, Ide Koichiro, Yamada Tomohiro, Kurosu Kenta, Matsuyama Yukihiro

机构信息

Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.

Department of Neurosurgery, Hue University of Medicine and Pharmacy, Hue, Vietnam.

出版信息

Nagoya J Med Sci. 2024 Nov;86(4):711-719. doi: 10.18999/nagjms.86.4.711.

DOI:10.18999/nagjms.86.4.711
PMID:39780926
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11704773/
Abstract

Ganglioneuromas are rare benign tumors that arise from the sympathetic nervous system. The presentation of tumors is variable and associated with adolescent thoracic scoliosis. Herein, we present two case reports and a review of literature. The two cases involved 10 and 13-year-old patients who were asymptomatic for muscle pain or weakness, and ganglioneuromas were incidentally detected through imaging screening. Both patients underwent a two-stage surgery. The first stage involved detachment of the tumor from the spinal cord and simultaneously performing deformity correction surgery from the posterior aspect. The second stage was resection of the ganglioneuroma through the anterior approach without neurological problems. A two-stage surgery was necessary to excise the tumor and correct the deformity, thereby avoiding neurological problems and concurrently establish a pathological diagnosis. Commencing with the posterior approach proved to be safe and was more effective.

摘要

神经节神经瘤是起源于交感神经系统的罕见良性肿瘤。肿瘤的表现多样,且与青少年胸椎侧弯有关。在此,我们呈现两例病例报告并进行文献综述。这两例病例涉及10岁和13岁的患者,他们没有肌肉疼痛或无力的症状,通过影像学筛查偶然发现了神经节神经瘤。两名患者均接受了两阶段手术。第一阶段包括将肿瘤与脊髓分离,并同时从后方进行畸形矫正手术。第二阶段通过前路切除神经节神经瘤,未出现神经问题。为切除肿瘤并矫正畸形,有必要进行两阶段手术,从而避免神经问题并同时建立病理诊断。从后路开始手术被证明是安全且更有效的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/b7da76d7b4aa/2186-3326-86-0711-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/56c2616622c4/2186-3326-86-0711-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/3f1c9341b55a/2186-3326-86-0711-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/186588e02143/2186-3326-86-0711-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/b7da76d7b4aa/2186-3326-86-0711-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/56c2616622c4/2186-3326-86-0711-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/3f1c9341b55a/2186-3326-86-0711-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/186588e02143/2186-3326-86-0711-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c2a1/11704773/b7da76d7b4aa/2186-3326-86-0711-g004.jpg

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Diagnostics (Basel). 2023 Jun 27;13(13):2190. doi: 10.3390/diagnostics13132190.
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Lumbar Ganglioneuroma Presenting With Scoliosis.以脊柱侧弯为表现的腰椎神经节瘤
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BMC Med Imaging. 2021 Jul 22;21(1):114. doi: 10.1186/s12880-021-00643-y.
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