Kikuchi H, Watanabe M
Cancer Lett. 1985 Mar;26(2):201-6. doi: 10.1016/0304-3835(85)90027-8.
The effects of dietary phenobarbital (PB) on RNA polymerase II (nucleoside triphosphate: RNA nucleotidyltransferase, EC 2. 7. 7. 6) in the liver of male Sprague-Dawley rats previously administered diethylnitrosamine (DENA) were studied. When a diet containing 0.05% phenobarbital was administered, the activity of DNA-dependent RNA polymerase II in the liver nuclei of rats was temporarily increased 1 and 2 weeks after the onset of feeding and expressed to be relatively higher afterwards, compared with the activity in rats fed the control diets.
研究了膳食中苯巴比妥（PB）对先前给予二乙基亚硝胺（DENA）的雄性斯普拉格 - 道利大鼠肝脏中RNA聚合酶II（核苷三磷酸：RNA核苷酸转移酶，EC 2.7.7.6）的影响。当给予含0.05%苯巴比妥的饮食时，与喂食对照饮食的大鼠相比，喂食开始后1周和2周，大鼠肝细胞核中依赖DNA的RNA聚合酶II的活性暂时增加，且之后表现为相对较高。
