卡哈尔体的调控：与60S核糖体的意外联系。
Regulation of Cajal bodies: Unexpected connection to 60S ribosomes.
作者信息
Courvan Edward M C, Parker Roy R
机构信息
Department of Biochemistry, University of Colorado, Boulder, CO, USA.
Howard Hughes Medical Institute, University of Colorado , Boulder, CO, USA.
出版信息
J Cell Biol. 2025 Feb 3;224(2). doi: 10.1083/jcb.202501009. Epub 2025 Jan 9.
Abstract
Cajal bodies are essential sites for the biogenesis of small nuclear and nucleolar ribonucleoproteins. In this issue, Courvan and Parker discuss new work from Neugebauer and colleagues (https://doi.org/10.1083/jcb.202305081) that carefully profiles Cajal Body components and finds an unexpected role for 60S ribosomal proteins.
摘要
卡哈尔体是小核核糖核蛋白和核仁核糖核蛋白生物合成的重要场所。在本期中，库尔万和帕克讨论了纽格鲍尔及其同事的新研究（https://doi.org/10.1083/jcb.202305081），该研究仔细分析了卡哈尔体的组成成分，并发现了60S核糖体蛋白的一个意想不到的作用。
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