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诱发胃癌的环境因素:对风险及预防策略的见解

Environmental factors inducing gastric cancer: insights into risk and prevention strategies.

作者信息

He Puyi, Li Xiaomei, Zou Dan, Tang Futian, Chen Hao, Li Yumin

机构信息

The Second Hospital of Lanzhou University, Lanzhou, 730030, China.

Gansu Province Key Laboratory of Environmental Oncology, Lanzhou, 730030, China.

出版信息

Discov Oncol. 2025 Jan 9;16(1):25. doi: 10.1007/s12672-025-01771-5.

Abstract

Gastric cancer, a prevalent malignant tumor worldwide, poses a significant challenge to global health. Despite ongoing advancements in treatment methods, its high incidence and mortality rates remain concerning. Although progress in treating gastric cancer is encouraging, a more critical focus is on enhancing prevention efforts. Understanding the risk factors associated with gastric cancer is crucial for its prevention. This article summarizes the environmental factors related to the development of gastric cancer and their prevention, including: Living or working environment factors (air pollution, water quality, soil pollution, radiation, altitude, climate), dietary habits (meat, high-fat diet, high-salt diet), lifestyle habits (smoking, Drinking, sleep, coffee), and viral and bacterial exposures (Epstein-Barr virus, Human cytomegalovirus, Helicobacter pylori). Additionally, the article discusses current research directions and aims to provide a reference for researchers, paving the way for future preventive and therapeutic strategies.

摘要

胃癌是全球普遍存在的恶性肿瘤,对全球健康构成重大挑战。尽管治疗方法不断进步,但其高发病率和死亡率仍然令人担忧。虽然胃癌治疗取得的进展令人鼓舞,但更关键的重点是加强预防工作。了解与胃癌相关的危险因素对其预防至关重要。本文总结了与胃癌发生相关的环境因素及其预防措施,包括:生活或工作环境因素(空气污染、水质、土壤污染、辐射、海拔、气候)、饮食习惯(肉类、高脂肪饮食、高盐饮食)、生活方式习惯(吸烟、饮酒、睡眠、咖啡)以及病毒和细菌暴露(爱泼斯坦-巴尔病毒、人巨细胞病毒、幽门螺杆菌)。此外,本文还讨论了当前的研究方向,旨在为研究人员提供参考,为未来的预防和治疗策略铺平道路。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e4c7/11717776/90f60ddef4c1/12672_2025_1771_Fig1_HTML.jpg

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