Song Huishan, Ge Sheng, Li Ji, Jiao Chendao, Ran Linghua
School of Sports Science, Harbin Normal University, Harbin, China.
Central Hospital of Heilongjiang Provincial Prison Administration, Harbin, China.
PLoS One. 2025 Jan 9;20(1):e0314539. doi: 10.1371/journal.pone.0314539. eCollection 2025.
To explore the impact of aerobic and resistance training on walking and balance abilities (UPDRS-III, Gait Velocity, Mini-BESTest, and TUG) in individuals with Parkinson's disease (PD).
All articles published between the year of inception and July 2024 were obtained from PubMed, Embase, and Web of Science. Meta-analysis was conducted with RevMan 5.4.
Research from 15 randomized controlled trials, comprising 792 older patients with a diagnosis of PD, was included in the analysis. Aerobic training (AT) and Resistance training (RT) significantly improved UPDRS-III (AT, SMD = -5.69, 95% CI: -8.67 to -2.71, p = 0.0002, I2 = 82%; RT, SMD = -3.01, 95% CI: -4.89 to -1.12, p = 0.002, I2 = 0%) and Gait Velocity(AT, SMD = 0.88, 95% CI: 0.58 to 1.18, p < 0.00001, I2 = 42%; RT, SMD = 0.52, 95% CI: 0.10 to 0.94, p = 0.01, I2 = 55%). AT showed no difference in Mini-BESTest (AT, SMD = 2.12, 95% CI: -0.70 to 4.94, p = 0.14, I2 = 90%). RT showed no change in TUG (RT, SMD = -0.03, 95% CI: -1.60 to 1.54, p = 0.97, I2 = 63%).
Resistance training stood out as the most effective approach to boost performance on the mini-BESTest. Conversely, aerobic exercise proved to be superior for improving the UPDRS-III, gait velocity and TUG scores.
探讨有氧运动和抗阻训练对帕金森病（PD）患者步行和平衡能力（统一帕金森病评定量表第三部分[UPDRS-III]、步速、简短伯格平衡量表[Mini-BESTest]和定时起立步行测试[TUG]）的影响。
从PubMed、Embase和Web of Science获取自起始年份至2024年7月发表的所有文章。使用RevMan 5.4进行荟萃分析。
分析纳入了15项随机对照试验的研究，包括792名诊断为PD的老年患者。有氧运动（AT）和抗阻训练（RT）显著改善了UPDRS-III（AT，标准化均数差[SMD]=-5.69，95%置信区间[CI]：-8.67至-2.71，p=0.0002，I²=82%；RT，SMD=-3.01，95%CI：-4.89至-1.12，p=0.002，I²=0%）和步速（AT，SMD=0.88，95%CI：0.58至1.18，p<0.00001，I²=42%；RT，SMD=0.52，95%CI：0.10至0.94，p=0.01，I²=55%）。AT在Mini-BESTest方面无差异（AT，SMD=2.12，95%CI：-0.70至4.94，p=0.14，I²=90%）。RT在TUG方面无变化（RT，SMD=-0.03，95%CI：-1.60至1.54，p=0.97，I²=63%）。
抗阻训练是提高Mini-BESTest表现的最有效方法。相反，有氧运动在改善UPDRS-III、步速和TUG评分方面更具优势。
