Fu Whitney, Wagner Catherine M, Brescia Alexander A, Hawkins Robert B, Romano Matthew A, Ailawadi Gorav, Bolling Steven F
Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Ann Thorac Surg Short Rep. 2024 Jun 18;2(4):754-758. doi: 10.1016/j.atssr.2024.05.022. eCollection 2024 Dec.
The rate of permanent pacemaker implantation after tricuspid valve (TV) operation is thought to be high, with some studies quoting rates of 20% to 30%. We identified the rate of pacemaker implantation after TV operation at a high-volume regional reference center to better characterize the contemporary risk of pacemaker.
All adult patients without preexisting pacemakers undergoing TV operation from 2011 to 2022 were included. Patients were categorized by type of tricuspid operation and concomitant procedures. Bivariable analysis and multivariable logistic and Cox regression were performed to compare outcomes and to identify covariates independently associated with pacemaker implantation and long-term mortality.
A total of 1346 patients with no history of pacemaker underwent TV operation. The overall rate of pacemaker was 11% (142/1346), with a 9.2% (113/1235) pacemaker rate with TV repair vs 26% (29/111) rate with TV replacement ( < .001). For isolated TV operations, permanent pacemaker rate was 3.7% (5/135) for repairs vs 23% (18/79) for replacement ( < .001). Need for pacemaker implantation varied significantly by type of operation. Adjusting for patient and operative characteristics, combined aortic root and valve operation, combined mitral and tricuspid surgery, longer cross-clamp time, and tricuspid replacement were independent risk factors for pacemaker. There was no difference in long-term mortality between the groups.
In this large data series, the rate of pacemaker with any TV operation was 11% and ranged from 0% to 33% according to concomitant procedures. Contemporary risk of pacemaker after TV operation at a high-volume center may be lower than previously thought.
三尖瓣(TV)手术后永久性起搏器植入率被认为较高,一些研究报道的发生率为20%至30%。我们在一个高容量的区域参考中心确定了TV手术后起搏器植入率,以更好地描述当代起搏器风险。
纳入2011年至2022年所有未预先植入起搏器且接受TV手术的成年患者。患者按三尖瓣手术类型和同期手术进行分类。进行双变量分析以及多变量逻辑回归和Cox回归,以比较结果并确定与起搏器植入和长期死亡率独立相关的协变量。
共有1346例无起搏器植入史的患者接受了TV手术。起搏器总体植入率为11%(142/1346),TV修复术的起搏器植入率为9.2%(113/1235),而TV置换术的植入率为26%(29/111)(P<0.001)。对于单纯TV手术,修复术的永久性起搏器植入率为3.7%(5/135),置换术为23%(18/79)(P<0.001)。起搏器植入需求因手术类型而异。校正患者和手术特征后,主动脉根部和瓣膜联合手术、二尖瓣和三尖瓣联合手术、较长的主动脉阻断时间以及三尖瓣置换是起搏器植入的独立危险因素。两组之间的长期死亡率无差异。
在这个大数据系列中,任何TV手术的起搏器植入率为11%,根据同期手术情况,范围为0%至33%。高容量中心TV手术后当代起搏器风险可能低于先前认为的水平。