Sharma Kamal, Mohan Shilpi, Hossain S A, Shah Stuti, Konat Ashwati, Shah Komal, Mehta Shubh, Tavethia Jonsi Jayantkumar, Sarvaiya Jeel Narendra, Joshi Saumya, Shah Karan, Patel Dhruv Rakeshkumar, Patel Shlok
U N Mehta Institute of Cardiology and Research Centre, Ahmedabad, Gujarat, India.
Ashvattha Cardiac Care Centre, Apollo Clinic, Secunderabad, Telangana, India.
J Family Med Prim Care. 2024 Dec;13(12):5621-5625. doi: 10.4103/jfmpc.jfmpc_712_24. Epub 2024 Dec 9.
Cardiovascular diseases (CVDs) are one of the most prevalent causes of mortality worldwide, especially significant in low- and middle-income countries. Kyrgyzstan and India represent such nations that face a huge burden of CVD-related deaths globally. Understanding the prevalence of traditional cardiovascular risk factors (CVRFs) in these populations is critical for effective prevention and management strategies.
This is a multicentric, observational study where we compared the prevalence of CVRFs in high-risk populations from Kyrgyzstan and India. Data was collected from established ASCVD patients attending cardio-metabolic clinics at tertiary care centers between December 2021 and December 2023. Demographic characteristics and CVRFs, which encompassed diabetes, hypertension, lipid profile parameters, tobacco consumption, etc., were assessed. Statistical analysis was performed to identify significant differences between the cohorts.
A total of 1552 individuals (772 from Kyrgyzstan, 750 from India) were studied. The Kyrgyzstan cohort had a significantly higher mean age and a greater proportion of females compared to the Indian cohort. The prevalence of tobacco consumption, hypertension, and diabetes was significantly higher in Kyrgyzstan than in India. Lipid profile analysis revealed greater level of LDL, HDL, and total cholesterol in the Kyrgyzstan cohort. Conversely, triglyceride levels were lower in Kyrgyz individuals. The Kyrgyzstan cohort also demonstrated better left ventricular systolic function compared to the Indian cohort.
Our study highlights significant differences in the prevalence of traditional CVRFs between high-risk populations in Kyrgyzstan and India. Higher rates of tobacco consumption, hypertension, and diabetes in Kyrgyzstan signify the immediate need for targeted interventions to address these modifiable risk factors. Targeted public health programs focusing on these lifestyle modifications and efficacious management of CVRFs are crucial to reduce the burden of cardiovascular deaths in both countries.
心血管疾病（CVDs）是全球最常见的死亡原因之一，在低收入和中等收入国家尤为显著。吉尔吉斯斯坦和印度就是在全球面临与心血管疾病相关死亡巨大负担的国家。了解这些人群中传统心血管危险因素（CVRFs）的流行情况对于有效的预防和管理策略至关重要。
这是一项多中心观察性研究，我们比较了吉尔吉斯斯坦和印度高危人群中CVRFs的流行情况。数据收集自2021年12月至2023年12月在三级医疗中心心血管代谢诊所就诊的确诊动脉粥样硬化性心血管疾病（ASCVD）患者。评估了人口统计学特征和CVRFs，包括糖尿病、高血压、血脂参数、烟草消费等。进行了统计分析以确定队列之间的显著差异。
共研究了1552名个体（772名来自吉尔吉斯斯坦，750名来自印度）。与印度队列相比，吉尔吉斯斯坦队列的平均年龄显著更高，女性比例更大。吉尔吉斯斯坦的烟草消费、高血压和糖尿病患病率显著高于印度。血脂分析显示吉尔吉斯斯坦队列的低密度脂蛋白、高密度脂蛋白和总胆固醇水平更高。相反，吉尔吉斯斯坦人的甘油三酯水平较低。与印度队列相比，吉尔吉斯斯坦队列的左心室收缩功能也更好。
我们的研究突出了吉尔吉斯斯坦和印度高危人群中传统CVRFs流行情况的显著差异。吉尔吉斯斯坦较高的烟草消费、高血压和糖尿病发病率表明迫切需要针对性干预措施来解决这些可改变的危险因素。专注于这些生活方式改变和有效管理CVRFs的针对性公共卫生项目对于减轻两国心血管疾病死亡负担至关重要。
