人类抗凝血酶III结构基因定位于1号染色体q23 - 25区。
Assignment of the human antithrombin III structural gene to chromosome 1q23-25.
作者信息
Bock S C, Harris J F, Balazs I, Trent J M
出版信息
Cytogenet Cell Genet. 1985;39(1):67-9. doi: 10.1159/000132105.
PMID:3979120
Abstract
The human antithrombin III (ATIII) structural gene was mapped by in situ hybridization and quantitative analysis of ATIII gene dosage in DNA isolated from carriers of chromosome 1 deletions. These studies indicate that the ATIII structural gene maps to human chromosome q23-q25 and so is likely identical to AT3.
摘要
通过原位杂交以及对从1号染色体缺失携带者中分离出的DNA进行抗凝血酶III（ATIII）基因剂量的定量分析，对人类抗凝血酶III（ATIII）结构基因进行了定位。这些研究表明，ATIII结构基因定位于人类染色体q23 - q25，因此可能与AT3相同。
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