Sun Jiahao, Lu Shihang, Cheng Ming, Xue Nianting, Chen Shiqiang, Liu Guangzhou, Gao Yuanyuan, Lai Li, Dou Wenwen
Institute of Marine Science and Technology, Shandong University, Qingdao, Shandong 266237, China.
Aviation Key Laboratory of Science and Technology on Advanced Surface Engineering, AVIC Manufacturing Technology Institute, Beijing 100024, China.
Bioelectrochemistry. 2025 Jun;163:108890. doi: 10.1016/j.bioelechem.2024.108890. Epub 2025 Jan 3.
Microbiologically influenced corrosion (MIC) affects offshore production activities severely. Although adding biocides is a simple method, it can cause environmental damage over time. Using green biocide enhancers is a viable strategy to reduce the amount of biocides. In this study, four novel peptides, named Peptide T/Tc/Ts/Tcs, were designed by a natural peptide extracted from the Arctic sea squirt to enhance the efficacy of tetrakis hydroxymethyl phosphonium sulfate (THPS) in mitigating the biocorrosion of EH36 steel caused by Desulfovibrio ferrophilus. The combination of 40 ppm THPS and 100 nM Peptide T/Tc/Ts/Tcs reduced the corrosion rates of EH36 steel by 68 %, 71 %, 86 %, and 90 % after the 7-d incubation, respectively. Notably, 40 ppm THPS + 100 nM Peptide Ts/Tcs achieved similar antimicrobial and biocorrosion mitigation effects as 100 ppm THPS. It suggests that optimizing the cationic and hydrophobic properties of peptides could enhance the bactericidal properties of biocides.
微生物影响的腐蚀（MIC）严重影响海上生产活动。虽然添加杀菌剂是一种简单的方法，但随着时间的推移，它会对环境造成破坏。使用绿色杀菌剂增效剂是减少杀菌剂用量的可行策略。在本研究中，通过从北极海鞘中提取的天然肽设计了四种新型肽，命名为肽T/Tc/Ts/Tcs，以提高四羟甲基硫酸磷（THPS）减轻嗜铁脱硫弧菌引起的EH36钢生物腐蚀的功效。在7天的培养后，40 ppm的THPS与100 nM的肽T/Tc/Ts/Tcs组合分别使EH36钢的腐蚀速率降低了68%、71%、86%和90%。值得注意的是，40 ppm的THPS + 100 nM的肽Ts/Tcs实现了与100 ppm的THPS相似的抗菌和减轻生物腐蚀的效果。这表明优化肽的阳离子和疏水性质可以增强杀菌剂的杀菌性能。
