Sánchez-Díaz Carola T, Fejerman Laura, Peterson Caryn, Basu Sanjib, Fitzgibbon Marian, Rauscher Garth H
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, 60612, USA.
Division of Cancer Control and Population Science, University of Puerto Rico Comprehensive Cancer Center, San Juan, 00925, Puerto Rico.
Cancer Causes Control. 2025 Jun;36(6):567-575. doi: 10.1007/s10552-024-01952-7. Epub 2025 Jan 11.
The prevalence of obesity, a crucial risk factor for breast cancer, is markedly higher among Hispanic women. The interaction between ethnic enclaves and neighborhood socioeconomic status (SES) as a determinant of this disparity warrants further research. We aimed to identify neighborhood profiles based on ethnic enclaves and socioeconomic status to evaluate the association with obesity among Hispanic women in the metropolitan Chicago region.
We used a convenience sample of 24,884 Hispanic women over age 40 who obtained breast imaging from the largest healthcare organization in Chicago between 2010 and 2017. We conducted LPA to characterize neighborhood composition based on tract indicators of ethnic enclaves, disadvantage, and affluence. Multivariate linear and multinomial logistic regression models were used to evaluate the association of neighborhood profiles with BMI.
The LPA model identified four latent profiles, labeled based on their most significant characteristic as "middling," "disadvantage" "ethnic enclaves," and "affluent". Close to 50% of women in the disadvantage profile were obese and obese class II. Women in the disadvantage profile had the highest relative risk of being obese II (OR: 2.74 CI 95% 2.23, 3.36), compared to women in the middling profile. Women in the ethnic enclave and affluent profile were positively and negatively associated with obesity, respectively.
Using LPA to group individuals according to their combined traits provides empirical evidence to strengthen our understanding of how neighborhoods influence obesity in Hispanic women. The study findings suggest that ethnic enclaves, that are also disadvantage, are associated with obesity in Hispanic women.
肥胖是乳腺癌的一个关键风险因素，在西班牙裔女性中的患病率明显更高。民族飞地与邻里社会经济地位（SES）之间的相互作用作为这种差异的一个决定因素，值得进一步研究。我们旨在根据民族飞地和社会经济地位确定邻里概况，以评估与芝加哥大都市区西班牙裔女性肥胖之间的关联。
我们使用了一个便利样本，其中包括24884名年龄在40岁以上的西班牙裔女性，她们在2010年至2017年期间从芝加哥最大的医疗保健机构进行了乳房成像检查。我们进行潜在类别分析（LPA），以根据民族飞地、劣势和富裕程度的区域指标来描述邻里构成。多元线性和多项逻辑回归模型用于评估邻里概况与体重指数（BMI）之间的关联。
潜在类别分析模型确定了四个潜在概况，根据其最显著特征分别标记为“中等”“劣势”“民族飞地”和“富裕”。处于劣势概况的女性中近50%为肥胖和重度肥胖。与处于中等概况的女性相比，处于劣势概况的女性患重度肥胖的相对风险最高（比值比：2.74，95%置信区间2.23，3.36）。处于民族飞地概况和富裕概况的女性分别与肥胖呈正相关和负相关。
使用潜在类别分析根据个体的综合特征进行分组，为加强我们对邻里如何影响西班牙裔女性肥胖的理解提供了实证证据。研究结果表明，处于劣势的民族飞地与西班牙裔女性肥胖有关。
